TopFIND 4.0

A1L4K1: Fibronectin type III and SPRY domain-containing protein 2

General Information

Protein names
- Fibronectin type III and SPRY domain-containing protein 2
- SPRY domain-containing protein 1
Gene names FSD2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID A1L4K1

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEEESGEELG LDRSTPKDFH FYHMDLYDSE DRLHLFPEEN TRMRKVVQAE MANESRGAGD 
        70         80         90        100        110        120 
GKAQRDLQEE VDELVHLYGL EDDHELGDEF VDENIPRTGV SEYPPYMMKR RDPAREQRDW 
       130        140        150        160        170        180 
RLSGEAAEAE DLGFGGWGSA GQCQDLREAY RYTHGRASEE YECYVIPEEE DEEEAADVFC 
       190        200        210        220        230        240 
VTCKTPIRAF QKVFDEHKEH EVIPLNEALE SAKDEIHKNM YKLEKQIIEM ENFANHLEEV 
       250        260        270        280        290        300 
FITVEENFGK QEQNFESHYN EILETLAQKY EEKIQALGEK KKEKLEALYG QLVSCGENLD 
       310        320        330        340        350        360 
TCKELMETIE EMCHEEKVDF IKDAVAMADR LGKFLKTKTD VEISAQPEFE DQTLDFSDVE 
       370        380        390        400        410        420 
QLMGSINTIP APSAPVINPQ VPNSATGSSV RVCWSLYSDD TVESYQLSYR PVQDSSPGTD 
       430        440        450        460        470        480 
QAEFTVTVKE TYCSVTNLVP NTQYEFWVTA HNRAGPSPSS ERAVYMTAPS PPIIKTKEIR 
       490        500        510        520        530        540 
SCEEAVLICW ESGNLNPVDS YTVELTQAES PEASGVTESV VGIPTCESVV QLQPGRSYII 
       550        560        570        580        590        600 
YVRALNMGGP SVRSEPATVH TIGSYFRLNK DTCHPWLTIS EDGLTAVRSE RRTPARELSP 
       610        620        630        640        650        660 
SDTHFTRCVA VMGNLIPVRG HHYWEVEVDE HLDYRVGVAF ADVRKQEDLG ANCLSWCMRH 
       670        680        690        700        710        720 
TFASSRHKYE FLHNRTTPDI RITVPPKKIG ILLDYEHSKL SFFNVDLSQH LYTFSCQLHE 
       730        740    
FVHPCFSLEK PGCLKVHNGI SMPKHVTFY

Isoforms

- Isoform 2 of Fibronectin type III and SPRY domain-containing protein 2

Sequence View

        10         20         30         40         50         60 
MEEESGEELG LDRSTPKDFH FYHMDLYDSE DRLHLFPEEN TRMRKVVQAE MANESRGAGD 
        70         80         90        100        110        120 
GKAQRDLQEE VDELVHLYGL EDDHELGDEF VDENIPRTGV SEYPPYMMKR RDPAREQRDW 
       130        140        150        160        170        180 
RLSGEAAEAE DLGFGGWGSA GQCQDLREAY RYTHGRASEE YECYVIPEEE DEEEAADVFC 
       190        200        210        220        230        240 
VTCKTPIRAF QKVFDEHKEH EVIPLNEALE SAKDEIHKNM YKLEKQIIEM ENFANHLEEV 
       250        260        270        280        290        300 
FITVEENFGK QEQNFESHYN EILETLAQKY EEKIQALGEK KKEKLEALYG QLVSCGENLD 
       310        320        330        340        350        360 
TCKELMETIE EMCHEEKVDF IKDAVAMADR LGKFLKTKTD VEISAQPEFE DQTLDFSDVE 
       370        380        390        400        410        420 
QLMGSINTIP APSAPVINPQ VPNSATGSSV RVCWSLYSDD TVESYQLSYR PVQDSSPGTD 
       430        440        450        460        470        480 
QAEFTVTVKE TYCSVTNLVP NTQYEFWVTA HNRAGPSPSS ERAVYMTAPS PPIIKTKEIR 
       490        500        510        520        530        540 
SCEEAVLICW ESGNLNPVDS YTVELTQAES PEASGVTESV VGIPTCESVV QLQPGRSYII 
       550        560        570        580        590        600 
YVRALNMGGP SVRSEPATVH TIGSYFRLNK DTCHPWLTIS EDGLTAVRSE RRTPARELSP 
       610        620        630        640        650        660 
SDTHFTRCVA VMGNLIPVRG HHYWEVEVDE HLDYRVGVAF ADVRKQEDLG ANCLSWCMRH 
       670        680        690        700        710        720 
TFASSRHKYE FLHNRTTPDI RITVPPKKIG ILLDYEHSKL SFFNVDLSQH LYTFSCQLHE 
       730        740    
FVHPCFSLEK PGCLKVHNGI SMPKHVTFY



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    A1L4K1-1-unknown MEEESG... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    A1L4K1-1-unknown MEEESG... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt75504

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)