TopFIND 4.0

B0YJ81: Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 {ECO:0000305}

General Information

Protein names
- Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 {ECO:0000305}
- 4.2.1.134 {ECO:0000269|PubMed:18554506, ECO:0000269|PubMed:23933735}
- 3-hydroxyacyl-CoA dehydratase 1 {ECO:0000303|PubMed:18554506}
- HACD1 {ECO:0000303|PubMed:15164054}
- Cementum-attachment protein {ECO:0000303|PubMed:22067203}
- CAP {ECO:0000303|PubMed:22067203}
- Protein-tyrosine phosphatase-like member A {ECO:0000312|HGNC:HGNC:9639}
Gene names PTPLA
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID B0YJ81

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGRLTEAAAA GSGSRAAGWA GSPPTLLPLS PTSPRCAATM ASSDEDGTNG GASEAGEDRE 
        70         80         90        100        110        120 
APGERRRLGV LATAWLTFYD IAMTAGWLVL AIAMVRFYME KGTHRGLYKS IQKTLKFFQT 
       130        140        150        160        170        180 
FALLEIVHCL IGIVPTSVIV TGVQVSSRIF MVWLITHSIK PIQNEESVVL FLVAWTVTEI 
       190        200        210        220        230        240 
TRYSFYTFSL LDHLPYFIKW ARYNFFIILY PVGVAGELLT IYAALPHVKK TGMFSIRLPN 
       250        260        270        280    
KYNVSFDYYY FLLITMASYI PLFPQLYFHM LRQRRKVLHG EVIVEKDD

Isoforms

- Isoform 2 of Very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 1 - Isoform 2 of Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1

Sequence View

        10         20         30         40         50         60 
MGRLTEAAAA GSGSRAAGWA GSPPTLLPLS PTSPRCAATM ASSDEDGTNG GASEAGEDRE 
        70         80         90        100        110        120 
APGERRRLGV LATAWLTFYD IAMTAGWLVL AIAMVRFYME KGTHRGLYKS IQKTLKFFQT 
       130        140        150        160        170        180 
FALLEIVHCL IGIVPTSVIV TGVQVSSRIF MVWLITHSIK PIQNEESVVL FLVAWTVTEI 
       190        200        210        220        230        240 
TRYSFYTFSL LDHLPYFIKW ARYNFFIILY PVGVAGELLT IYAALPHVKK TGMFSIRLPN 
       250        260        270        280    
KYNVSFDYYY FLLITMASYI PLFPQLYFHM LRQRRKVLHG EVIVEKDD         10         20         30         40         50         60 
MGRLTEAAAA GSGSRAAGWA GSPPTLLPLS PTSPRCAATM ASSDEDGTNG GASEAGEDRE 
        70         80         90        100        110        120 
APGERRRLGV LATAWLTFYD IAMTAGWLVL AIAMVRFYME KGTHRGLYKS IQKTLKFFQT 
       130        140        150        160        170        180 
FALLEIVHCL IGIVPTSVIV TGVQVSSRIF MVWLITHSIK PIQNEESVVL FLVAWTVTEI 
       190        200        210        220        230        240 
TRYSFYTFSL LDHLPYFIKW ARYNFFIILY PVGVAGELLT IYAALPHVKK TGMFSIRLPN 
       250        260        270        280    
KYNVSFDYYY FLLITMASYI PLFPQLYFHM LRQRRKVLHG EVIVEKDD



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    B0YJ81-1-unknown MGRLTE... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    B0YJ81-1-unknown MGRLTE... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt76714

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...VEKDD 288 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)