TopFIND 4.0

O15503: Insulin-induced gene 1 protein

General Information

Protein names
- Insulin-induced gene 1 protein
- INSIG-1
Gene names INSIG1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O15503

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPRLHDHFWS CSCAHSARRR GPPRASAAGL AAKVGEMINV SVSGPSLLAA HGAPDADPAP 
        70         80         90        100        110        120 
RGRSAAMSGP EPGSPYPNTW HHRLLQRSLV LFSVGVVLAL VLNLLQIQRN VTLFPEEVIA 
       130        140        150        160        170        180 
TIFSSAWWVP PCCGTAAAVV GLLYPCIDSH LGEPHKFKRE WASVMRCIAV FVGINHASAK 
       190        200        210        220        230        240 
LDFANNVQLS LTLAALSLGL WWTFDRSRSG LGLGITIAFL ATLITQFLVY NGVYQYTSPD 
       250        260        270    
FLYIRSWLPC IFFSGGVTVG NIGRQLAMGV PEKPHSD

Isoforms

- Isoform 2 of Insulin-induced gene 1 protein

Sequence View

        10         20         30         40         50         60 
MPRLHDHFWS CSCAHSARRR GPPRASAAGL AAKVGEMINV SVSGPSLLAA HGAPDADPAP 
        70         80         90        100        110        120 
RGRSAAMSGP EPGSPYPNTW HHRLLQRSLV LFSVGVVLAL VLNLLQIQRN VTLFPEEVIA 
       130        140        150        160        170        180 
TIFSSAWWVP PCCGTAAAVV GLLYPCIDSH LGEPHKFKRE WASVMRCIAV FVGINHASAK 
       190        200        210        220        230        240 
LDFANNVQLS LTLAALSLGL WWTFDRSRSG LGLGITIAFL ATLITQFLVY NGVYQYTSPD 
       250        260        270    
FLYIRSWLPC IFFSGGVTVG NIGRQLAMGV PEKPHSD



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O15503-1-unknown MPRLHD... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    O15503-1-unknown MPRLHD... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt77934

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...KPHSD 277 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)