TopFIND 4.0

O70167: Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma

General Information

Protein names
- Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma
- PI3K-C2-gamma
- PtdIns-3-kinase C2 subunit gamma
- 2.7.1.154
- Phosphoinositide 3-kinase-C2-gamma
Gene names Pik3c2g
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID O70167

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAYSWQTEPN RTEPQEDGSD TQQFHHTNQH LSSRQVRLGF DQLVEEINNK TPLSESEKEE 
        70         80         90        100        110        120 
DTYFVPDAPN LGSKWPSIYE THPRYFSEFT SQSPDSSQLR FGKLSAIGFN PAVLPTHQLI 
       130        140        150        160        170        180 
HEGASWRNPS GKYHGIEYPR FDALPPSSTG QGECNPQGQS GTKHHNYCGE HEGNLPHHHS 
       190        200        210        220        230        240 
SYSIDSIPNR EKRRSGDVNL VEPSLEFSKD SFLPRTSENV SVESTEPIGC PIEIVEVPQG 
       250        260        270        280        290        300 
SNKNLASFCN KVKKIRESYH ASDINSNSGK IWAITTAYPS RLFADTKFRV KISIDNSAQL 
       310        320        330        340        350        360 
LLLMPHANYL VKDLIAEILL LCANEPLSPK EYLLSVCGSE EFLQMDHSLG SHKIFQKNKS 
       370        380        390        400        410        420 
VIQLHLQKNR DTPGKLSRKS EDDHSPFHLN QLLEFTHIWK ISRQCLSTVM KKYNLHVEHL 
       430        440        450        460        470        480 
LKPQKDMEEK HLSSMVSGNQ HTSQPHVNNV LEEVKNICSV LGCIETKQVS DAVKELNLIL 
       490        500        510        520        530        540 
QRPSQNFHQN SETSKKGFIE RVTAELSRSI YQLIDVYCSS FCTDFQPVHT PGGVSHVHAG 
       550        560        570        580        590        600 
LQSHLSFTVC SLHNVPETWA HSYKAFSFSC WLTYAGKKLC QVKSCRPLPV TKSFSLLVNW 
       610        620        630        640        650        660 
NEIINFPLEI KSLPRESMLV IKLFGIDSAT HSTNLLAWTC LPLFPRQESV LGSRLFSVTL 
       670        680        690        700        710        720 
QSEPPIEMIA PGVWDGSQPS PLTLQIDFPD AGWEYLKPES EENRTDHEEP PRECLKHIAK 
       730        740        750        760        770        780 
LSQKKSPLLL SEEKRRYLWF YRLYCNNENS SLPLVLGSAP GWDEETVSEM HAILRRWTFS 
       790        800        810        820        830        840 
HPWEALGLLT SRFPDQDIRE VAVQQLDTLL TDELLDCLPQ LVQAVKFEWN LESPLVELLP 
       850        860        870        880        890        900 
RRPLQSIRVA HCLYWLLRDA QGEAYFKSWY QELLAALQFC AGEALNEELS KEQKLVKLLG 
       910        920        930        940        950        960 
DIGEKVKSAS DPQRKDVLKK EIGSLEEFFK DIKTCHLPLN PALCIKGIDR DACSYFTSNA 
       970        980        990       1000       1010       1020 
SPLKITFINA NPMGKNISVI FKAGDDLRQD MLALQIIQVM DNAWLQEGLD MQMITYGCLS 
      1030       1040       1050       1060       1070       1080 
TGRAQGFIEM VPDAVTLAKI HLHSGLIGPL KENTIKKWFS QHNHLKEDYE KALRNFFYSC 
      1090       1100       1110       1120       1130       1140 
AGWCVVTFIL GVCDRHNDNI MLTKSGHMFH IDFGKFLGHA QTFGGIKRDR APFIFTSEME 
      1150       1160       1170       1180       1190       1200 
YFITEGGKNI QHFQDFVELC CRAYNIVRKH SQLILSLLEM MLHAGLPELR GIEDLKYVHN 
      1210       1220       1230       1240       1250       1260 
NLRPQDTDLE ATSHFTKKIK ESLECFPVKL NNLIHTLAQM PALSLAKPAP QTLLQESCIL 
      1270       1280       1290       1300       1310       1320 
NKTRTIQRVT ILGFSKTHSN LYLMEVTCSD NRRSLTKKSF EQFYRLHSQM QKQFSSLALP 
      1330       1340       1350       1360       1370       1380 
EFPHWWHLPF TDSDHKRIRD LSHYVEQVLR GSYEVANSDC VLSFFLSEHI QPTLEDSPFV 
      1390       1400       1410       1420       1430       1440 
DPGENSLDKS PKVQLLMTYE DSRLTILVKH LKNIHLPDGS VPSAHVEIYL LPHPSEVRRK 
      1450       1460       1470       1480       1490       1500 
KTKCVPKCTD PTYNEIVVYD EVLGLQGHVL MLIVKSKTVF VGAVNIQLCS VPLNEEKWYP 
   
LGNSII

Isoforms

- Isoform 2 of Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma

Sequence View

        10         20         30         40         50         60 
MAYSWQTEPN RTEPQEDGSD TQQFHHTNQH LSSRQVRLGF DQLVEEINNK TPLSESEKEE 
        70         80         90        100        110        120 
DTYFVPDAPN LGSKWPSIYE THPRYFSEFT SQSPDSSQLR FGKLSAIGFN PAVLPTHQLI 
       130        140        150        160        170        180 
HEGASWRNPS GKYHGIEYPR FDALPPSSTG QGECNPQGQS GTKHHNYCGE HEGNLPHHHS 
       190        200        210        220        230        240 
SYSIDSIPNR EKRRSGDVNL VEPSLEFSKD SFLPRTSENV SVESTEPIGC PIEIVEVPQG 
       250        260        270        280        290        300 
SNKNLASFCN KVKKIRESYH ASDINSNSGK IWAITTAYPS RLFADTKFRV KISIDNSAQL 
       310        320        330        340        350        360 
LLLMPHANYL VKDLIAEILL LCANEPLSPK EYLLSVCGSE EFLQMDHSLG SHKIFQKNKS 
       370        380        390        400        410        420 
VIQLHLQKNR DTPGKLSRKS EDDHSPFHLN QLLEFTHIWK ISRQCLSTVM KKYNLHVEHL 
       430        440        450        460        470        480 
LKPQKDMEEK HLSSMVSGNQ HTSQPHVNNV LEEVKNICSV LGCIETKQVS DAVKELNLIL 
       490        500        510        520        530        540 
QRPSQNFHQN SETSKKGFIE RVTAELSRSI YQLIDVYCSS FCTDFQPVHT PGGVSHVHAG 
       550        560        570        580        590        600 
LQSHLSFTVC SLHNVPETWA HSYKAFSFSC WLTYAGKKLC QVKSCRPLPV TKSFSLLVNW 
       610        620        630        640        650        660 
NEIINFPLEI KSLPRESMLV IKLFGIDSAT HSTNLLAWTC LPLFPRQESV LGSRLFSVTL 
       670        680        690        700        710        720 
QSEPPIEMIA PGVWDGSQPS PLTLQIDFPD AGWEYLKPES EENRTDHEEP PRECLKHIAK 
       730        740        750        760        770        780 
LSQKKSPLLL SEEKRRYLWF YRLYCNNENS SLPLVLGSAP GWDEETVSEM HAILRRWTFS 
       790        800        810        820        830        840 
HPWEALGLLT SRFPDQDIRE VAVQQLDTLL TDELLDCLPQ LVQAVKFEWN LESPLVELLP 
       850        860        870        880        890        900 
RRPLQSIRVA HCLYWLLRDA QGEAYFKSWY QELLAALQFC AGEALNEELS KEQKLVKLLG 
       910        920        930        940        950        960 
DIGEKVKSAS DPQRKDVLKK EIGSLEEFFK DIKTCHLPLN PALCIKGIDR DACSYFTSNA 
       970        980        990       1000       1010       1020 
SPLKITFINA NPMGKNISVI FKAGDDLRQD MLALQIIQVM DNAWLQEGLD MQMITYGCLS 
      1030       1040       1050       1060       1070       1080 
TGRAQGFIEM VPDAVTLAKI HLHSGLIGPL KENTIKKWFS QHNHLKEDYE KALRNFFYSC 
      1090       1100       1110       1120       1130       1140 
AGWCVVTFIL GVCDRHNDNI MLTKSGHMFH IDFGKFLGHA QTFGGIKRDR APFIFTSEME 
      1150       1160       1170       1180       1190       1200 
YFITEGGKNI QHFQDFVELC CRAYNIVRKH SQLILSLLEM MLHAGLPELR GIEDLKYVHN 
      1210       1220       1230       1240       1250       1260 
NLRPQDTDLE ATSHFTKKIK ESLECFPVKL NNLIHTLAQM PALSLAKPAP QTLLQESCIL 
      1270       1280       1290       1300       1310       1320 
NKTRTIQRVT ILGFSKTHSN LYLMEVTCSD NRRSLTKKSF EQFYRLHSQM QKQFSSLALP 
      1330       1340       1350       1360       1370       1380 
EFPHWWHLPF TDSDHKRIRD LSHYVEQVLR GSYEVANSDC VLSFFLSEHI QPTLEDSPFV 
      1390       1400       1410       1420       1430       1440 
DPGENSLDKS PKVQLLMTYE DSRLTILVKH LKNIHLPDGS VPSAHVEIYL LPHPSEVRRK 
      1450       1460       1470       1480       1490       1500 
KTKCVPKCTD PTYNEIVVYD EVLGLQGHVL MLIVKSKTVF VGAVNIQLCS VPLNEEKWYP 
   
LGNSII



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O70167-1-unknown MAYSWQ... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...GNSII 1506 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...GNSII 1506 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt79644

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)