TopFIND 4.0

O88563: Canalicular multispecific organic anion transporter 2

General Information

Protein names
- Canalicular multispecific organic anion transporter 2
- ATP-binding cassette sub-family C member 3
- MRP-like protein 2
- MLP-2
- Multidrug resistance-associated protein 3
Gene names Abcc3
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID O88563

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDRLCGSGEL GSKFWDSNLT VYTNTPDLTP CFQNSLLAWV PCIYLWAALP CYLFYLRHHR 
        70         80         90        100        110        120 
LGYIVLSCLS RLKTALGVLL WCISWVDLFY SFHGLVHGSS PAPVFFITPL LVGITMLLAT 
       130        140        150        160        170        180 
LLIQYERLRG VRSSGVLIIF WLLCVICAII PFRSKILLAL AEGKILDPFR FTTFYIYFAL 
       190        200        210        220        230        240 
VLCAFILSCF QEKPPLFSPE NLDTNPCPEA SAGFFSRLSF WWFTKLAILG YRRPLEDSDL 
       250        260        270        280        290        300 
WSLSEEDCSH KVVQRLLEAW QKQQTQASGP QTAALEPKIA GEDEVLLKAR PKTKKPSFLR 
       310        320        330        340        350        360 
ALVRTFTSSL LMGACFKLIQ DLSPSSTHSC SASSSGLFRP HGPYWWGFLL AGLMFVSSTM 
       370        380        390        400        410        420 
QTLILHQHYH CIFVMALRIR TAIIGVIYRK ALTITNSVKR EYTVGEMVNL MSVDAQRFMD 
       430        440        450        460        470        480 
VSPFINLLWS APLQVILAIY FLWQILGPSA LAGVAVIVLL IPLNGAVSMK MKTYQVQQMK 
       490        500        510        520        530        540 
FKDSRIKLMS EILNGIKVLK LYAWEPTFLE QVEGIRQGEL QLLRKGAYLQ AISTFIWVCT 
       550        560        570        580        590        600 
PFMVTLITLG VYVCVDKNNV LDAEKAFVSL SLFNILKIPL NLLPQLISGM TQTSVSLKRI 
       610        620        630        640        650        660 
QDFLNQDELD PQCVERKTIS PGRAITIHNG TFSWSKDLPP TLHSINIQIP KGALVAVVGP 
       670        680        690        700        710        720 
VGCGKSSLVS ALLGEMEKLE GAVSVKGSVA YVPQQAWIQN CTLQENVLFG QPMNPKRYQQ 
       730        740        750        760        770        780 
ALETCALLAD LDVLPGGDQT EIGEKGINLS GGQRQRVSLA RAVYSDANIF LLDDPLSAVD 
       790        800        810        820        830        840 
SHVAKHIFDQ VIGPEGVLAG KTRVLVTHGI SFLPQTDFII VLADGQITEM GHYSELLQHD 
       850        860        870        880        890        900 
GSFANFLRNY APDENQEANE GVLQHANEEV LLLEDTLSTH TDLTDTEPAI YEVRKQFMRE 
       910        920        930        940        950        960 
MSSLSSEGEG QNRPVLKRYT SSLEKEVPAT QTKETGALIK EEIAETGNVK LSVYWDYAKS 
       970        980        990       1000       1010       1020 
VGLCTTLFIC LLYAGQNAVA IGANVWLSAW TNDVEEHGQQ NNTSVRLGVY ATLGILQGLL 
      1030       1040       1050       1060       1070       1080 
VMLSAFTMVV GAIQAARLLH TALLHNQIRA PQSFFDTTPS GRILNRFSKD IYVIHEVLAP 
      1090       1100       1110       1120       1130       1140 
TILMLFNSFY TSISTIVVIV ASTPLFCVVV LPLAVFYGFV QRFYVATSRQ LKRLESVSRS 
      1150       1160       1170       1180       1190       1200 
PIFSHFSETV TGTSVIRAYG RVQDFKVLSD AKVDSNQKTT YPYIASNRWL GVHVEFVGNC 
      1210       1220       1230       1240       1250       1260 
VVLFSALFAV IGRNSLNPGL VGLSVSYALQ VTLSLNWMIR TLSDLESNII AVERVKEYSK 
      1270       1280       1290       1300       1310       1320 
TETEAPWVLE SNRAPEGWPR SGVVEFRNYS VRYRPGLELV LKNLTLHVQG GEKVGIVGRT 
      1330       1340       1350       1360       1370       1380 
GAGKSSMTLC LFRILEAAEG EIFIDGLNVA HIGLHDLRSQ LTIIPQDPIL FSGTLRMNLD 
      1390       1400       1410       1420       1430       1440 
PFGRYSDEDI WRTLELSHLS AFVSSQPTGL DFQCSEGGDN LSVGQRQLVC LARALLRKSR 
      1450       1460       1470       1480       1490       1500 
VLVLDEATAA IDLETDDLIQ GTIRTQFEDC TVLTIAHRLN TIMDYNRVLV LDKGVVAEFD 
      1510       1520    
SPVNLIAAGG IFYGMAKDAG LA

Isoforms



Sequence View



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O88563-1-unknown MDRLCG... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...DAGLA 1522 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)