P10606: Cytochrome c oxidase subunit 5B, mitochondrial

General Information

Protein names	- Cytochrome c oxidase subunit 5B, mitochondrial - Cytochrome c oxidase polypeptide Vb
Gene names	COX5B
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P10606

12 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MASRLLRGAG TLAAQALRAR GPSGAAAMRS MASGGGVPTD EEQATGLERE IMLAAKKGLD
        70         80         90        100        110        120
PYNVLAPKGA SGTREDPNLV PSISNKRIVG CICEEDNTSV VWFWLHKGEA QRCPRCGAHY

KLVPQQLAH

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

12 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P10606-30-	SMASGG...	30		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P10606-30-	SMASGG...	30		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P10606-30-	SMASGG...	30		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P10606-30-	SMASGG...	30		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P10606-30-	SMASGG...	30		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P10606-31-unknown	MASGGG...	31		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P10606-31-	MASGGG...	31		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P10606-31-	MASGGG...	31		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P10606-31-	MASGGG...	31		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P10606-31-	MASGGG...	31		Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
P10606-31-	MASGGG...	31		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P10606-31-	MASGGG...	31		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P10606-31-	MASGGG...	31		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P10606-31-	MASGGG...	31		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P10606-31-	MASGGG...	31		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P10606-31-	MASGGG...	31		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P10606-31-	MASGGG...	31		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P10606-32-unknown	ASGGGV...	32	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P10606-32-unknown	ASGGGV...	32		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P10606-32-unknown	ASGGGV...	32		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P10606-32-	ASGGGV...	32		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P10606-32-	ASGGGV...	32		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P10606-32-	ASGGGV...	32		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P10606-32-	ASGGGV...	32		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_CD95	23264352
P10606-32-	ASGGGV...	32		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P10606-32-	ASGGGV...	32		Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
P10606-32-	ASGGGV...	32		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P10606-32-	ASGGGV...	32		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P10606-32-	ASGGGV...	32		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P10606-32-	ASGGGV...	32		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P10606-32-	ASGGGV...	32		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P10606-32-	ASGGGV...	32		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P10606-32-	ASGGGV...	32		Subtiligase Based Positive Selection		Wells	RMPI_untreated	23264352
P10606-32-	ASGGGV...	32		Subtiligase Based Positive Selection		Wells	THP_untreated	23264352
P10606-32-	ASGGGV...	32		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P10606-33-	SGGGVP...	33		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P10606-33-	SGGGVP...	33		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P10606-33-	SGGGVP...	33		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P10606-34-	GGGVPT...	34		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P10606-34-	GGGVPT...	34		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P10606-34-	GGGVPT...	34		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P10606-34-	GGGVPT...	34		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P10606-35-	GGVPTD...	35		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P10606-35-	GGVPTD...	35		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P10606-36-	GVPTDE...	36		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P10606-36-	GVPTDE...	36		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P10606-36-	GVPTDE...	36		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P10606-57-unknown	KGLDPY...	57		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P10606-57-	KGLDPY...	57		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P10606-57-	KGLDPY...	57		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P10606-57-	KGLDPY...	57		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P10606-57-	KGLDPY...	57		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P10606-58-	GLDPYN...	58		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P10606-58-	GLDPYN...	58		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...QQLAH	129	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)