TopFIND 4.0

P16152: Carbonyl reductase [NADPH] 1

General Information

Protein names
- Carbonyl reductase NADPH] 1
- 1.1.1.184
- 15-hydroxyprostaglandin dehydrogenase NADP(+)]
- 1.1.1.197
- NADPH-dependent carbonyl reductase 1
- Prostaglandin 9-ketoreductase
- Prostaglandin-E(2) 9-reductase
- 1.1.1.189
- Short chain dehydrogenase/reductase family 21C member 1
Gene names CBR1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P16152

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSSGIHVALV TGGNKGIGLA IVRDLCRLFS GDVVLTARDV TRGQAAVQQL QAEGLSPRFH 
        70         80         90        100        110        120 
QLDIDDLQSI RALRDFLRKE YGGLDVLVNN AGIAFKVADP TPFHIQAEVT MKTNFFGTRD 
       130        140        150        160        170        180 
VCTELLPLIK PQGRVVNVSS IMSVRALKSC SPELQQKFRS ETITEEELVG LMNKFVEDTK 
       190        200        210        220        230        240 
KGVHQKEGWP SSAYGVTKIG VTVLSRIHAR KLSEQRKGDK ILLNACCPGW VRTDMAGPKA 
       250        260        270    
TKSPEEGAET PVYLALLPPD AEGPHGQFVS EKRVEQW

Isoforms

- Isoform 2 of Carbonyl reductase [NADPH] 1

Sequence View

        10         20         30         40         50         60 
MSSGIHVALV TGGNKGIGLA IVRDLCRLFS GDVVLTARDV TRGQAAVQQL QAEGLSPRFH 
        70         80         90        100        110        120 
QLDIDDLQSI RALRDFLRKE YGGLDVLVNN AGIAFKVADP TPFHIQAEVT MKTNFFGTRD 
       130        140        150        160        170        180 
VCTELLPLIK PQGRVVNVSS IMSVRALKSC SPELQQKFRS ETITEEELVG LMNKFVEDTK 
       190        200        210        220        230        240 
KGVHQKEGWP SSAYGVTKIG VTVLSRIHAR KLSEQRKGDK ILLNACCPGW VRTDMAGPKA 
       250        260        270    
TKSPEEGAET PVYLALLPPD AEGPHGQFVS EKRVEQW



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Evidence Names:


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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P16152-2-unknown MSSGIH... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P16152-1-unknown MSSGIH... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt69476
    P16152-2-Acetylation SSGIHV... 2 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P16152-2-Acetylation SSGIHV... 2 acetylation- inferred from isoform by sequence similarity unknown TopFIND inferred from TNt110079

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RVEQW 277 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)