TopFIND 4.0

P17246: Transforming growth factor beta-1 proprotein

General Information

Protein names
- Transforming growth factor beta-1 proprotein
- Latency-associated peptide
- LAP
- Transforming growth factor beta-1
- TGF-beta-1
Gene names Tgfb1
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID P17246

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPPSGLRLLP LLLPLPWLLV LTPGRPAAGL STCKTIDMEL VKRKRIEAIR GQILSKLRLA 
        70         80         90        100        110        120 
SPPSQGEVPP GPLPEAVLAL YNSTRDRVAG ESADPEPEPE ADYYAKEVTR VLMVDRNNAI 
       130        140        150        160        170        180 
YDKTKDITHS IYMFFNTSDI REAVPEPPLL SRAELRLQRF KSTVEQHVEL YQKYSNNSWR 
       190        200        210        220        230        240 
YLGNRLLTPT DTPEWLSFDV TGVVRQWLNQ GDGIQGFRFS AHCSCDSKDN VLHVEINGIS 
       250        260        270        280        290        300 
PKRRGDLGTI HDMNRPFLLL MATPLERAQH LHSSRHRRAL DTNYCFSSTE KNCCVRQLYI 
       310        320        330        340        350        360 
DFRKDLGWKW IHEPKGYHAN FCLGPCPYIW SLDTQYSKVL ALYNQHNPGA SASPCCVPQA 
       370        380        390    
LEPLPIVYYV GRKPKVEQLS NMIVRSCKCS 

Isoforms



Sequence View



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P17246-30-unknown LSTCKT... 30 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P17246-279-unknown ALDTNY... 279 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SRHRRA 278 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...SCKCS 390 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)