P29218: Inositol monophosphatase 1

General Information

Protein names	- Inositol monophosphatase 1 - IMP 1 - IMPase 1 - 3.1.3.25 {ECO:0000269\|PubMed:1377913, ECO:0000269\|PubMed:17068342, ECO:0000269\|PubMed:8068620, ECO:0000269\|PubMed:8718889, ECO:0000269\|PubMed:9462881} - D-galactose 1-phosphate phosphatase {ECO:0000303\|PubMed:9462881} - 3.1.3.94 {ECO:0000269\|PubMed:9462881} - Inositol-1(or 4)-monophosphatase 1 - Lithium-sensitive myo-inositol monophosphatase A1
Gene names	IMPA1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P29218

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Inositol monophosphatase 1 - Isoform 3 of Inositol monophosphatase 1

Sequence View

        10         20         30         40         50         60
MADPWQECMD YAVTLARQAG EVVCEAIKNE MNVMLKSSPV DLVTATDQKV EKMLISSIKE
        70         80         90        100        110        120
KYPSHSFIGE ESVAAGEKSI LTDNPTWIID PIDGTTNFVH RFPFVAVSIG FAVNKKIEFG
       130        140        150        160        170        180
VVYSCVEGKM YTARKGKGAF CNGQKLQVSQ QEDITKSLLV TELGSSRTPE TVRMVLSNME
       190        200        210        220        230        240
KLFCIPVHGI RSVGTAAVNM CLVATGGADA YYEMGIHCWD VAGAGIIVTE AGGVLMDVTG
       250        260        270
GPFDLMSRRV IAANNRILAE RIAKEIQVIP LQRDDED         10         20         30         40         50         60
MADPWQECMD YAVTLARQAG EVVCEAIKNE MNVMLKSSPV DLVTATDQKV EKMLISSIKE
        70         80         90        100        110        120
KYPSHSFIGE ESVAAGEKSI LTDNPTWIID PIDGTTNFVH RFPFVAVSIG FAVNKKIEFG
       130        140        150        160        170        180
VVYSCVEGKM YTARKGKGAF CNGQKLQVSQ QEDITKSLLV TELGSSRTPE TVRMVLSNME
       190        200        210        220        230        240
KLFCIPVHGI RSVGTAAVNM CLVATGGADA YYEMGIHCWD VAGAGIIVTE AGGVLMDVTG
       250        260        270
GPFDLMSRRV IAANNRILAE RIAKEIQVIP LQRDDED

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P29218-1-unknown	MADPWQ...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P29218-1-unknown	MADPWQ...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt77856
P29218-1-unknown	MADPWQ...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt97727
P29218-2-acetylation	ADPWQE...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
P29218-2-acetylation	ADPWQE...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P29218-2-acetylation	ADPWQE...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt163259
P29218-2-acetylation	ADPWQE...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt163258

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...RDDED	277	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...RDDED	277	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt73475

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)