TopFIND 4.0

P30136: Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089}

General Information

Protein names
- Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089}
- 4.1.99.17 {ECO:0000255|HAMAP-Rule:MF_00089}
- Hydroxymethylpyrimidine phosphate synthase {ECO:0000255|HAMAP-Rule:MF_00089}
- HMP-P synthase {ECO:0000255|HAMAP-Rule:MF_00089}
- HMP-phosphate synthase {ECO:0000255|HAMAP-Rule:MF_00089}
- HMPP synthase {ECO:0000255|HAMAP-Rule:MF_00089}
- Thiamine biosynthesis protein ThiC {ECO:0000255|HAMAP-Rule:MF_00089}
Gene names thiC
Organism Escherichia coli
Protease Family
Protease ID
Chromosome location
UniProt ID P30136

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSATKLTRRE QRARAQHFID TLEGTAFPNS KRIYITGTHP GVRVPMREIQ LSPTLIGGSK 
        70         80         90        100        110        120 
EQPQYEENEA IPVYDTSGPY GDPQIAINVQ QGLAKLRQPW IDARGDTEEL TVRSSDYTKA 
       130        140        150        160        170        180 
RLADDGLDEL RFSGVLTPKR AKAGRRVTQL HYARQGIITP EMEFIAIREN MGRERIRSEV 
       190        200        210        220        230        240 
LRHQHPGMSF GAHLPENITA EFVRDEVAAG RAIIPANINH PESEPMIIGR NFLVKVNANI 
       250        260        270        280        290        300 
GNSAVTSSIE EEVEKLVWST RWGADTVMDL STGRYIHETR EWILRNSPVP IGTVPIYQAL 
       310        320        330        340        350        360 
EKVNGIAEDL TWEAFRDTLL EQAEQGVDYF TIHAGVLLRY VPMTAKRLTG IVSRGGSIMA 
       370        380        390        400        410        420 
KWCLSHHQEN FLYQHFREIC EICAAYDVSL SLGDGLRPGS IQDANDEAQF AELHTLGELT 
       430        440        450        460        470        480 
KIAWEYDVQV MIEGPGHVPM QMIRRNMTEE LEHCHEAPFY TLGPLTTDIA PGYDHFTSGI 
       490        500        510        520        530        540 
GAAMIGWFGC AMLCYVTPKE HLGLPNKEDV KQGLITYKIA AHAADLAKGH PGAQIRDNAM 
       550        560        570        580        590        600 
SKARFEFRWE DQFNLALDPF TARAYHDETL PQESGKVAHF CSMCGPKFCS MKISQEVRDY 
       610        620        630    
AATQTIEMGM ADMSENFRAR GGEIYLRKEE A

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P30136-1-unknown MSATKL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RKEEA 631 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)