TopFIND 4.0

P31652: Sodium-dependent serotonin transporter

General Information

Protein names
- Sodium-dependent serotonin transporter
- SERT {ECO:0000303|PubMed:16870614}
- 5HT transporter
- 5HTT
- Solute carrier family 6 member 4
Gene names Slc6a4
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID P31652

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
METTPLNSQK VLSECKDRED CQENGVLQKG VPTTADRAEP SQISNGYSAV PSTSAGDEAS 
        70         80         90        100        110        120 
HSIPAATTTL VAEIRQGERE TWGKKMDFLL SVIGYAVDLG NIWRFPYICY QNGGGAFLLP 
       130        140        150        160        170        180 
YTIMAIFGGI PLFYMELALG QYHRNGCISI WRKICPIFKG IGYAICIIAF YIASYYNTII 
       190        200        210        220        230        240 
AWALYYLISS LTDRLPWTSC TNSWNTGNCT NYFAQDNITW TLHSTSPAEE FYLRHVLQIH 
       250        260        270        280        290        300 
QSKGLQDLGT ISWQLTLCIV LIFTVIYFSI WKGVKTSGKV VWVTATFPYI VLSVLLVRGA 
       310        320        330        340        350        360 
TLPGAWRGVV FYLKPNWQKL LETGVWVDAA AQIFFSLGPG FGVLLAFASY NKFNNNCYQD 
       370        380        390        400        410        420 
ALVTSVVNCM TSFVSGFVIF TVLGYMAEMR NEDVSEVAKD AGPSLLFITY AEAIANMPAS 
       430        440        450        460        470        480 
TFFAIIFFLM LITLGLDSTF AGLEGVITAV LDEFPHIWAK RREWFVLIVV ITCVLGSLLT 
       490        500        510        520        530        540 
LTSGGAYVVT LLEEYATGPA VLTVALIEAV AVSWFYGITQ FCSDVKEMLG FSPGWFWRIC 
       550        560        570        580        590        600 
WVAISPLFLL FIICSFLMSP PQLRLFQYNY PHWSIVLGYC IGMSSVICIP TYIIYRLIST 
       610        620        630    
PGTLKERIIK SITPETPTEI PCGDIRMNAV 

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P31652-1-unknown METTPL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RMNAV 630 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)