P50440: Glycine amidinotransferase, mitochondrial

General Information

Protein names	- Glycine amidinotransferase, mitochondrial - 2.1.4.1 {ECO:0000269\|PubMed:27233232, ECO:0000269\|PubMed:3800397} - L-arginine:glycine amidinotransferase - Transamidinase
Gene names	GATM
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P50440

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Glycine amidinotransferase, mitochondrial - Isoform 3 of Glycine amidinotransferase, mitochondrial

Sequence View

        10         20         30         40         50         60
MLRVRCLRGG SRGAEAVHYI GSRLGRTLTG WVQRTFQSTQ AATASSRNSC AADDKATEPL
        70         80         90        100        110        120
PKDCPVSSYN EWDPLEEVIV GRAENACVPP FTIEVKANTY EKYWPFYQKQ GGHYFPKDHL
       130        140        150        160        170        180
KKAVAEIEEM CNILKTEGVT VRRPDPIDWS LKYKTPDFES TGLYSAMPRD ILIVVGNEII
       190        200        210        220        230        240
EAPMAWRSRF FEYRAYRSII KDYFHRGAKW TTAPKPTMAD ELYNQDYPIH SVEDRHKLAA
       250        260        270        280        290        300
QGKFVTTEFE PCFDAADFIR AGRDIFAQRS QVTNYLGIEW MRRHLAPDYR VHIISFKDPN
       310        320        330        340        350        360
PMHIDATFNI IGPGIVLSNP DRPCHQIDLF KKAGWTIITP PTPIIPDDHP LWMSSKWLSM
       370        380        390        400        410        420
NVLMLDEKRV MVDANEVPIQ KMFEKLGITT IKVNIRNANS LGGGFHCWTC DVRRRGTLQS

YLD         10         20         30         40         50         60
MLRVRCLRGG SRGAEAVHYI GSRLGRTLTG WVQRTFQSTQ AATASSRNSC AADDKATEPL
        70         80         90        100        110        120
PKDCPVSSYN EWDPLEEVIV GRAENACVPP FTIEVKANTY EKYWPFYQKQ GGHYFPKDHL
       130        140        150        160        170        180
KKAVAEIEEM CNILKTEGVT VRRPDPIDWS LKYKTPDFES TGLYSAMPRD ILIVVGNEII
       190        200        210        220        230        240
EAPMAWRSRF FEYRAYRSII KDYFHRGAKW TTAPKPTMAD ELYNQDYPIH SVEDRHKLAA
       250        260        270        280        290        300
QGKFVTTEFE PCFDAADFIR AGRDIFAQRS QVTNYLGIEW MRRHLAPDYR VHIISFKDPN
       310        320        330        340        350        360
PMHIDATFNI IGPGIVLSNP DRPCHQIDLF KKAGWTIITP PTPIIPDDHP LWMSSKWLSM
       370        380        390        400        410        420
NVLMLDEKRV MVDANEVPIQ KMFEKLGITT IKVNIRNANS LGGGFHCWTC DVRRRGTLQS

YLD

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P50440-1-unknown	MLRVRC...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt75747
P50440-38-	STQAAT...	38		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P50440-38-	STQAAT...	38		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P50440-38-	STQAAT...	38		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P50440-38-	STQAAT...	38		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P50440-38-	STQAAT...	38		Subtiligase Based Positive Selection		Wells	THP_untreated	23264352
P50440-38-unknown	STQAAT...	38	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P50440-38-unknown	STQAAT...	38		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P50440-38-unknown	STQAAT...	38	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt115353
P50440-38-unknown	STQAAT...	38	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt115352
P50440-38-unknown	STQAAT...	38	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...QSYLD	423	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...QSYLD	423	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt71364

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)