TopFIND 4.0

P54256: Huntingtin-associated protein 1

General Information

Protein names
- Huntingtin-associated protein 1
- HAP-1
Gene names Hap1
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID P54256

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRPKDQVQSS AGDGTGSGDP ATGTPTTQPA ADPAPEPSAE PKPAPAQGTG SGQKSGSRTK 
        70         80         90        100        110        120 
TGGSFCRSRI RGDSDAPWTR YIFQGPYGPR ATGLGTGRAE GIWKTPAAYI GRRPGVSGPE 
       130        140        150        160        170        180 
RAAFIRELQE ALCPNPLPRK KITEDDIKVM LYLLEEKERD LNTAARIGQS LVKQNSVLME 
       190        200        210        220        230        240 
ENNKLETMLG SAREEILHLR KQVNLRDDLL QLYSDSDDDE EDEEDEEEEE GEEEEREGQR 
       250        260        270        280        290        300 
DQDQQHDHPY GAPKPPPKAE TLHHCPQLEA LKQKLKLLEE ENDHLREEAS HLDNLEDKEQ 
       310        320        330        340        350        360 
MLILECVEQF SEASQQMAEL SEVLVLRLEG YERQQKEITQ LQAEITKLQQ RCQSYGAQTE 
       370        380        390        400        410        420 
KLQQQLASEK GVHPESLRAG SHMQDYGSRP RERQEDGKSH RQRSSMPAGS VTHYGYSVPL 
       430        440        450        460        470        480 
DALPSFPETL AEELRTSLRK FITDPAYFME RCDTRCREER KKEQGTMPPP PVQDLKPPED 
       490        500        510        520        530        540 
FEAPEELVPE EELGAIEEVG TAEDGPAEET EQASEETEAW EEVEPEVDEA TRMNVVVSAL 
       550        560        570        580        590        600 
EASGLGPSHL DMKYVLQQLS NWQDAHSKRQ QKQKVVPKDS PAPQQQTNMG GGIVEQQPIV 
       610        620    
PTQDSQRLEE DRATHSPSAR EEEGPSGAT

Isoforms

- Isoform A of Huntingtin-associated protein 1

Sequence View

        10         20         30         40         50         60 
MRPKDQVQSS AGDGTGSGDP ATGTPTTQPA ADPAPEPSAE PKPAPAQGTG SGQKSGSRTK 
        70         80         90        100        110        120 
TGGSFCRSRI RGDSDAPWTR YIFQGPYGPR ATGLGTGRAE GIWKTPAAYI GRRPGVSGPE 
       130        140        150        160        170        180 
RAAFIRELQE ALCPNPLPRK KITEDDIKVM LYLLEEKERD LNTAARIGQS LVKQNSVLME 
       190        200        210        220        230        240 
ENNKLETMLG SAREEILHLR KQVNLRDDLL QLYSDSDDDE EDEEDEEEEE GEEEEREGQR 
       250        260        270        280        290        300 
DQDQQHDHPY GAPKPPPKAE TLHHCPQLEA LKQKLKLLEE ENDHLREEAS HLDNLEDKEQ 
       310        320        330        340        350        360 
MLILECVEQF SEASQQMAEL SEVLVLRLEG YERQQKEITQ LQAEITKLQQ RCQSYGAQTE 
       370        380        390        400        410        420 
KLQQQLASEK GVHPESLRAG SHMQDYGSRP RERQEDGKSH RQRSSMPAGS VTHYGYSVPL 
       430        440        450        460        470        480 
DALPSFPETL AEELRTSLRK FITDPAYFME RCDTRCREER KKEQGTMPPP PVQDLKPPED 
       490        500        510        520        530        540 
FEAPEELVPE EELGAIEEVG TAEDGPAEET EQASEETEAW EEVEPEVDEA TRMNVVVSAL 
       550        560        570        580        590        600 
EASGLGPSHL DMKYVLQQLS NWQDAHSKRQ QKQKVVPKDS PAPQQQTNMG GGIVEQQPIV 
       610        620    
PTQDSQRLEE DRATHSPSAR EEEGPSGAT



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(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P54256-1-unknown MRPKDQ... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P54256-1-unknown MRPKDQ... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt192739

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PSGAT 629 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)