TopFIND 4.0

P56581: G/T mismatch-specific thymine DNA glycosylase

General Information

Protein names
- G/T mismatch-specific thymine DNA glycosylase
- 3.2.2.29
- C-JUN leucine zipper interactive protein JZA-3
- Thymine-DNA glycosylase
Gene names Tdg
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P56581

4

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDAEAARSYS LEQVQALYSF PFQQMMAEVP NMAVTTGQQV PAVAPNMATV TEQQVPEDAP 
        70         80         90        100        110        120 
VQEPAPEAPK RRKRKPRAAE PQEPVEPKKP ATSKKSGKST KSKEKQEKIT DAFKVKRKVD 
       130        140        150        160        170        180 
RFNGVSEAEL LTKTLPDILT FNLDIVIIGI NPGLMAAYKG HHYPGPGNHF WKCLFMSGLS 
       190        200        210        220        230        240 
EVQLNHMDDH TLPGKYGIGF TNMVERTTPG SKDLSSKEFR EGGRILVQKL QKYQPRIAVF 
       250        260        270        280        290        300 
NGKCIYEIFS KEVFGVKVKN LEFGLQPHKI PDTETLCYVM PSSSARCAQF PRAQDKVHYY 
       310        320        330        340        350        360 
IKLKDLRDQL KGIERNADVQ EVQYTFDLQL AQEDAKKMAV KEEKYDPGYE AAYGGAYGEN 
       370        380        390        400        410        420 
PCNGEPCGIA SNGLTAHSAE PRGEAAPSDV PNGQWMAQSF AEQIPSFNNC GTREQEEESH 
   
A

Isoforms

- Isoform 2 of G/T mismatch-specific thymine DNA glycosylase

Sequence View

        10         20         30         40         50         60 
MDAEAARSYS LEQVQALYSF PFQQMMAEVP NMAVTTGQQV PAVAPNMATV TEQQVPEDAP 
        70         80         90        100        110        120 
VQEPAPEAPK RRKRKPRAAE PQEPVEPKKP ATSKKSGKST KSKEKQEKIT DAFKVKRKVD 
       130        140        150        160        170        180 
RFNGVSEAEL LTKTLPDILT FNLDIVIIGI NPGLMAAYKG HHYPGPGNHF WKCLFMSGLS 
       190        200        210        220        230        240 
EVQLNHMDDH TLPGKYGIGF TNMVERTTPG SKDLSSKEFR EGGRILVQKL QKYQPRIAVF 
       250        260        270        280        290        300 
NGKCIYEIFS KEVFGVKVKN LEFGLQPHKI PDTETLCYVM PSSSARCAQF PRAQDKVHYY 
       310        320        330        340        350        360 
IKLKDLRDQL KGIERNADVQ EVQYTFDLQL AQEDAKKMAV KEEKYDPGYE AAYGGAYGEN 
       370        380        390        400        410        420 
PCNGEPCGIA SNGLTAHSAE PRGEAAPSDV PNGQWMAQSF AEQIPSFNNC GTREQEEESH 
   
A



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(REFRESH)

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Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...EESHA 421 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...EESHA 421 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt87393

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)