P57071: PR domain zinc finger protein 15 {ECO:0000305}
| Protein names | - PR domain zinc finger protein 15 {ECO:0000305} - 2.1.1.- {ECO:0000305} - PR domain-containing protein 15 {ECO:0000305} - Zinc finger protein 298 |
|---|---|
| Gene names | PRDM15 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | P57071 |
5
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MPRRRPPASG AAQFPERIAT RSPDPIPLCT FQRQPRAAPV QPPCRLFFVT FAGCGHRWRS
70 80 90 100 110 120
ESKPGWISRS RSGIALRAAR PPGSSPPRPA APRPPPPGGV VAEAPGDVVI PRPRVQPMRV
130 140 150 160 170 180
ARGGPWTPNP AFREAESWSQ IGNQRVSEQL LETSLGNEVS DTEPLSPASA GLRRNPALPP
190 200 210 220 230 240
GPFAQNFSWG NQENLPPALG KIANGGGTGA GKAECGYETE SHLLEPHEIP LNVNTHKFSD
250 260 270 280 290 300
CEFPYEFCTV CFSPFKLLGM SGVEGVWNQH SRSASMHTFL NHSATGIREA GCRKDMPVSE
310 320 330 340 350 360
MAEDGSEEIM FIWCEDCSQY HDSECPELGP VVMVKDSFVL SRARSWPASG HVHTQAGQGM
370 380 390 400 410 420
RGYEDRDRAD PQQLPEAVPA GLVRRLSGQQ LPCRSTLTWG RLCHLVAQGR SSLPPNLEIR
430 440 450 460 470 480
RLEDGAEGVF AITQLVKRTQ FGPFESRRVA KWEKESAFPL KVFQKDGHPV CFDTSNEDDC
490 500 510 520 530 540
NWMMLVRPAA EAEHQNLTAY QHGSDVYFTT SRDIPPGTEL RVWYAAFYAK KMDKPMLKQA
550 560 570 580 590 600
GSGVHAAGTP ENSAPVESEP SQWACKVCSA TFLELQLLNE HLLGHLEQAK SLPPGSQSEA
610 620 630 640 650 660
AAPEKEQDTP RGEPPAVPES ENVATKEQKK KPRRGRKPKV SKAEQPLVIV EDKEPTEQVA
670 680 690 700 710 720
EIITEVPPDE PVSATPDERI MELVLGKLAT TTTDTSSVPK FTHHQNNTIT LKRSLILSSR
730 740 750 760 770 780
HGIRRKLIKQ LGEHKRVYQC NICSKIFQNS SNLSRHVRSH GDKLFKCEEC AKLFSRKESL
790 800 810 820 830 840
KQHVSYKHSR NEVDGEYRYR CGTCEKTFRI ESALEFHNCR TDDKTFQCEM CFRFFSTNSN
850 860 870 880 890 900
LSKHKKKHGD KKFACEVCSK MFYRKDVMLD HQRRHLEGVR RVKREDLEAG GENLVRYKKE
910 920 930 940 950 960
PSGCPVCGKV FSCRSNMNKH LLTHGDKKYT CEICGRKFFR VDVLRDHIHV HFKDIALMDD
970 980 990 1000 1010 1020
HQREEFIGKI GISSEENDDN SDESADSEPH KYSCKRCQLT FGRGKEYLKH IMEVHKEKGY
1030 1040 1050 1060 1070 1080
GCSICNRRFA LKATYHAHMV IHRENLPDPN VQKYIHPCEI CGRIFNSIGN LERHKLIHTG
1090 1100 1110 1120 1130 1140
VKSHACEQCG KSFARKDMLK EHMRVHDNVR EYLCAECGKG MKTKHALRHH MKLHKGIKEY
1150 1160 1170 1180 1190 1200
ECKECHRRFA QKVNMLKHCK RHTGIKDFMC ELCGKTFSER NTMETHKLIH TVGKQWTCSV
1210 1220 1230 1240 1250 1260
CDKKYVTEYM LQKHVQLTHD KVEAQSCQLC GTKVSTRASM SRHMRRKHPE VLAVRIDDLD
1270 1280 1290 1300 1310 1320
HLPETTTIDA SSIGIVQPEL TLEQEDLAEG KHGKAAKRSH KRKQKPEEEA GAPVPEDATF
1330 1340 1350 1360 1370 1380
SEYSEKETEF TGSVGDETNS AVQSIQQVVV TLGDPNVTTP SSSVGLTNIT VTPITTAAAT
1390 1400 1410 1420 1430 1440
QFTNLQPVAV GHLTTPERQL QLDNSILTVT FDTVSGSAML HNRQNDVQIH PQPEASNPQS
1450 1460 1470 1480 1490 1500
VAHFINLTTL VNSITPLGSQ LSDQHPLTWR AVPQTDVLPP SQPQAPPQQA AQPQVQAEQQ
QQQMYSY
Isoforms
- Isoform 2 of PR domain zinc finger protein 15 - Isoform 3 of PR domain zinc finger protein 15 - Isoform 4 of PR domain zinc finger protein 15 - Isoform 5 of PR domain zinc finger protein 15Sequence View
10 20 30 40 50 60
MPRRRPPASG AAQFPERIAT RSPDPIPLCT FQRQPRAAPV QPPCRLFFVT FAGCGHRWRS
70 80 90 100 110 120
ESKPGWISRS RSGIALRAAR PPGSSPPRPA APRPPPPGGV VAEAPGDVVI PRPRVQPMRV
130 140 150 160 170 180
ARGGPWTPNP AFREAESWSQ IGNQRVSEQL LETSLGNEVS DTEPLSPASA GLRRNPALPP
190 200 210 220 230 240
GPFAQNFSWG NQENLPPALG KIANGGGTGA GKAECGYETE SHLLEPHEIP LNVNTHKFSD
250 260 270 280 290 300
CEFPYEFCTV CFSPFKLLGM SGVEGVWNQH SRSASMHTFL NHSATGIREA GCRKDMPVSE
310 320 330 340 350 360
MAEDGSEEIM FIWCEDCSQY HDSECPELGP VVMVKDSFVL SRARSWPASG HVHTQAGQGM
370 380 390 400 410 420
RGYEDRDRAD PQQLPEAVPA GLVRRLSGQQ LPCRSTLTWG RLCHLVAQGR SSLPPNLEIR
430 440 450 460 470 480
RLEDGAEGVF AITQLVKRTQ FGPFESRRVA KWEKESAFPL KVFQKDGHPV CFDTSNEDDC
490 500 510 520 530 540
NWMMLVRPAA EAEHQNLTAY QHGSDVYFTT SRDIPPGTEL RVWYAAFYAK KMDKPMLKQA
550 560 570 580 590 600
GSGVHAAGTP ENSAPVESEP SQWACKVCSA TFLELQLLNE HLLGHLEQAK SLPPGSQSEA
610 620 630 640 650 660
AAPEKEQDTP RGEPPAVPES ENVATKEQKK KPRRGRKPKV SKAEQPLVIV EDKEPTEQVA
670 680 690 700 710 720
EIITEVPPDE PVSATPDERI MELVLGKLAT TTTDTSSVPK FTHHQNNTIT LKRSLILSSR
730 740 750 760 770 780
HGIRRKLIKQ LGEHKRVYQC NICSKIFQNS SNLSRHVRSH GDKLFKCEEC AKLFSRKESL
790 800 810 820 830 840
KQHVSYKHSR NEVDGEYRYR CGTCEKTFRI ESALEFHNCR TDDKTFQCEM CFRFFSTNSN
850 860 870 880 890 900
LSKHKKKHGD KKFACEVCSK MFYRKDVMLD HQRRHLEGVR RVKREDLEAG GENLVRYKKE
910 920 930 940 950 960
PSGCPVCGKV FSCRSNMNKH LLTHGDKKYT CEICGRKFFR VDVLRDHIHV HFKDIALMDD
970 980 990 1000 1010 1020
HQREEFIGKI GISSEENDDN SDESADSEPH KYSCKRCQLT FGRGKEYLKH IMEVHKEKGY
1030 1040 1050 1060 1070 1080
GCSICNRRFA LKATYHAHMV IHRENLPDPN VQKYIHPCEI CGRIFNSIGN LERHKLIHTG
1090 1100 1110 1120 1130 1140
VKSHACEQCG KSFARKDMLK EHMRVHDNVR EYLCAECGKG MKTKHALRHH MKLHKGIKEY
1150 1160 1170 1180 1190 1200
ECKECHRRFA QKVNMLKHCK RHTGIKDFMC ELCGKTFSER NTMETHKLIH TVGKQWTCSV
1210 1220 1230 1240 1250 1260
CDKKYVTEYM LQKHVQLTHD KVEAQSCQLC GTKVSTRASM SRHMRRKHPE VLAVRIDDLD
1270 1280 1290 1300 1310 1320
HLPETTTIDA SSIGIVQPEL TLEQEDLAEG KHGKAAKRSH KRKQKPEEEA GAPVPEDATF
1330 1340 1350 1360 1370 1380
SEYSEKETEF TGSVGDETNS AVQSIQQVVV TLGDPNVTTP SSSVGLTNIT VTPITTAAAT
1390 1400 1410 1420 1430 1440
QFTNLQPVAV GHLTTPERQL QLDNSILTVT FDTVSGSAML HNRQNDVQIH PQPEASNPQS
1450 1460 1470 1480 1490 1500
VAHFINLTTL VNSITPLGSQ LSDQHPLTWR AVPQTDVLPP SQPQAPPQQA AQPQVQAEQQ
QQQMYSY
10 20 30 40 50 60
MPRRRPPASG AAQFPERIAT RSPDPIPLCT FQRQPRAAPV QPPCRLFFVT FAGCGHRWRS
70 80 90 100 110 120
ESKPGWISRS RSGIALRAAR PPGSSPPRPA APRPPPPGGV VAEAPGDVVI PRPRVQPMRV
130 140 150 160 170 180
ARGGPWTPNP AFREAESWSQ IGNQRVSEQL LETSLGNEVS DTEPLSPASA GLRRNPALPP
190 200 210 220 230 240
GPFAQNFSWG NQENLPPALG KIANGGGTGA GKAECGYETE SHLLEPHEIP LNVNTHKFSD
250 260 270 280 290 300
CEFPYEFCTV CFSPFKLLGM SGVEGVWNQH SRSASMHTFL NHSATGIREA GCRKDMPVSE
310 320 330 340 350 360
MAEDGSEEIM FIWCEDCSQY HDSECPELGP VVMVKDSFVL SRARSWPASG HVHTQAGQGM
370 380 390 400 410 420
RGYEDRDRAD PQQLPEAVPA GLVRRLSGQQ LPCRSTLTWG RLCHLVAQGR SSLPPNLEIR
430 440 450 460 470 480
RLEDGAEGVF AITQLVKRTQ FGPFESRRVA KWEKESAFPL KVFQKDGHPV CFDTSNEDDC
490 500 510 520 530 540
NWMMLVRPAA EAEHQNLTAY QHGSDVYFTT SRDIPPGTEL RVWYAAFYAK KMDKPMLKQA
550 560 570 580 590 600
GSGVHAAGTP ENSAPVESEP SQWACKVCSA TFLELQLLNE HLLGHLEQAK SLPPGSQSEA
610 620 630 640 650 660
AAPEKEQDTP RGEPPAVPES ENVATKEQKK KPRRGRKPKV SKAEQPLVIV EDKEPTEQVA
670 680 690 700 710 720
EIITEVPPDE PVSATPDERI MELVLGKLAT TTTDTSSVPK FTHHQNNTIT LKRSLILSSR
730 740 750 760 770 780
HGIRRKLIKQ LGEHKRVYQC NICSKIFQNS SNLSRHVRSH GDKLFKCEEC AKLFSRKESL
790 800 810 820 830 840
KQHVSYKHSR NEVDGEYRYR CGTCEKTFRI ESALEFHNCR TDDKTFQCEM CFRFFSTNSN
850 860 870 880 890 900
LSKHKKKHGD KKFACEVCSK MFYRKDVMLD HQRRHLEGVR RVKREDLEAG GENLVRYKKE
910 920 930 940 950 960
PSGCPVCGKV FSCRSNMNKH LLTHGDKKYT CEICGRKFFR VDVLRDHIHV HFKDIALMDD
970 980 990 1000 1010 1020
HQREEFIGKI GISSEENDDN SDESADSEPH KYSCKRCQLT FGRGKEYLKH IMEVHKEKGY
1030 1040 1050 1060 1070 1080
GCSICNRRFA LKATYHAHMV IHRENLPDPN VQKYIHPCEI CGRIFNSIGN LERHKLIHTG
1090 1100 1110 1120 1130 1140
VKSHACEQCG KSFARKDMLK EHMRVHDNVR EYLCAECGKG MKTKHALRHH MKLHKGIKEY
1150 1160 1170 1180 1190 1200
ECKECHRRFA QKVNMLKHCK RHTGIKDFMC ELCGKTFSER NTMETHKLIH TVGKQWTCSV
1210 1220 1230 1240 1250 1260
CDKKYVTEYM LQKHVQLTHD KVEAQSCQLC GTKVSTRASM SRHMRRKHPE VLAVRIDDLD
1270 1280 1290 1300 1310 1320
HLPETTTIDA SSIGIVQPEL TLEQEDLAEG KHGKAAKRSH KRKQKPEEEA GAPVPEDATF
1330 1340 1350 1360 1370 1380
SEYSEKETEF TGSVGDETNS AVQSIQQVVV TLGDPNVTTP SSSVGLTNIT VTPITTAAAT
1390 1400 1410 1420 1430 1440
QFTNLQPVAV GHLTTPERQL QLDNSILTVT FDTVSGSAML HNRQNDVQIH PQPEASNPQS
1450 1460 1470 1480 1490 1500
VAHFINLTTL VNSITPLGSQ LSDQHPLTWR AVPQTDVLPP SQPQAPPQQA AQPQVQAEQQ
QQQMYSY
10 20 30 40 50 60
MPRRRPPASG AAQFPERIAT RSPDPIPLCT FQRQPRAAPV QPPCRLFFVT FAGCGHRWRS
70 80 90 100 110 120
ESKPGWISRS RSGIALRAAR PPGSSPPRPA APRPPPPGGV VAEAPGDVVI PRPRVQPMRV
130 140 150 160 170 180
ARGGPWTPNP AFREAESWSQ IGNQRVSEQL LETSLGNEVS DTEPLSPASA GLRRNPALPP
190 200 210 220 230 240
GPFAQNFSWG NQENLPPALG KIANGGGTGA GKAECGYETE SHLLEPHEIP LNVNTHKFSD
250 260 270 280 290 300
CEFPYEFCTV CFSPFKLLGM SGVEGVWNQH SRSASMHTFL NHSATGIREA GCRKDMPVSE
310 320 330 340 350 360
MAEDGSEEIM FIWCEDCSQY HDSECPELGP VVMVKDSFVL SRARSWPASG HVHTQAGQGM
370 380 390 400 410 420
RGYEDRDRAD PQQLPEAVPA GLVRRLSGQQ LPCRSTLTWG RLCHLVAQGR SSLPPNLEIR
430 440 450 460 470 480
RLEDGAEGVF AITQLVKRTQ FGPFESRRVA KWEKESAFPL KVFQKDGHPV CFDTSNEDDC
490 500 510 520 530 540
NWMMLVRPAA EAEHQNLTAY QHGSDVYFTT SRDIPPGTEL RVWYAAFYAK KMDKPMLKQA
550 560 570 580 590 600
GSGVHAAGTP ENSAPVESEP SQWACKVCSA TFLELQLLNE HLLGHLEQAK SLPPGSQSEA
610 620 630 640 650 660
AAPEKEQDTP RGEPPAVPES ENVATKEQKK KPRRGRKPKV SKAEQPLVIV EDKEPTEQVA
670 680 690 700 710 720
EIITEVPPDE PVSATPDERI MELVLGKLAT TTTDTSSVPK FTHHQNNTIT LKRSLILSSR
730 740 750 760 770 780
HGIRRKLIKQ LGEHKRVYQC NICSKIFQNS SNLSRHVRSH GDKLFKCEEC AKLFSRKESL
790 800 810 820 830 840
KQHVSYKHSR NEVDGEYRYR CGTCEKTFRI ESALEFHNCR TDDKTFQCEM CFRFFSTNSN
850 860 870 880 890 900
LSKHKKKHGD KKFACEVCSK MFYRKDVMLD HQRRHLEGVR RVKREDLEAG GENLVRYKKE
910 920 930 940 950 960
PSGCPVCGKV FSCRSNMNKH LLTHGDKKYT CEICGRKFFR VDVLRDHIHV HFKDIALMDD
970 980 990 1000 1010 1020
HQREEFIGKI GISSEENDDN SDESADSEPH KYSCKRCQLT FGRGKEYLKH IMEVHKEKGY
1030 1040 1050 1060 1070 1080
GCSICNRRFA LKATYHAHMV IHRENLPDPN VQKYIHPCEI CGRIFNSIGN LERHKLIHTG
1090 1100 1110 1120 1130 1140
VKSHACEQCG KSFARKDMLK EHMRVHDNVR EYLCAECGKG MKTKHALRHH MKLHKGIKEY
1150 1160 1170 1180 1190 1200
ECKECHRRFA QKVNMLKHCK RHTGIKDFMC ELCGKTFSER NTMETHKLIH TVGKQWTCSV
1210 1220 1230 1240 1250 1260
CDKKYVTEYM LQKHVQLTHD KVEAQSCQLC GTKVSTRASM SRHMRRKHPE VLAVRIDDLD
1270 1280 1290 1300 1310 1320
HLPETTTIDA SSIGIVQPEL TLEQEDLAEG KHGKAAKRSH KRKQKPEEEA GAPVPEDATF
1330 1340 1350 1360 1370 1380
SEYSEKETEF TGSVGDETNS AVQSIQQVVV TLGDPNVTTP SSSVGLTNIT VTPITTAAAT
1390 1400 1410 1420 1430 1440
QFTNLQPVAV GHLTTPERQL QLDNSILTVT FDTVSGSAML HNRQNDVQIH PQPEASNPQS
1450 1460 1470 1480 1490 1500
VAHFINLTTL VNSITPLGSQ LSDQHPLTWR AVPQTDVLPP SQPQAPPQQA AQPQVQAEQQ
QQQMYSY
10 20 30 40 50 60
MPRRRPPASG AAQFPERIAT RSPDPIPLCT FQRQPRAAPV QPPCRLFFVT FAGCGHRWRS
70 80 90 100 110 120
ESKPGWISRS RSGIALRAAR PPGSSPPRPA APRPPPPGGV VAEAPGDVVI PRPRVQPMRV
130 140 150 160 170 180
ARGGPWTPNP AFREAESWSQ IGNQRVSEQL LETSLGNEVS DTEPLSPASA GLRRNPALPP
190 200 210 220 230 240
GPFAQNFSWG NQENLPPALG KIANGGGTGA GKAECGYETE SHLLEPHEIP LNVNTHKFSD
250 260 270 280 290 300
CEFPYEFCTV CFSPFKLLGM SGVEGVWNQH SRSASMHTFL NHSATGIREA GCRKDMPVSE
310 320 330 340 350 360
MAEDGSEEIM FIWCEDCSQY HDSECPELGP VVMVKDSFVL SRARSWPASG HVHTQAGQGM
370 380 390 400 410 420
RGYEDRDRAD PQQLPEAVPA GLVRRLSGQQ LPCRSTLTWG RLCHLVAQGR SSLPPNLEIR
430 440 450 460 470 480
RLEDGAEGVF AITQLVKRTQ FGPFESRRVA KWEKESAFPL KVFQKDGHPV CFDTSNEDDC
490 500 510 520 530 540
NWMMLVRPAA EAEHQNLTAY QHGSDVYFTT SRDIPPGTEL RVWYAAFYAK KMDKPMLKQA
550 560 570 580 590 600
GSGVHAAGTP ENSAPVESEP SQWACKVCSA TFLELQLLNE HLLGHLEQAK SLPPGSQSEA
610 620 630 640 650 660
AAPEKEQDTP RGEPPAVPES ENVATKEQKK KPRRGRKPKV SKAEQPLVIV EDKEPTEQVA
670 680 690 700 710 720
EIITEVPPDE PVSATPDERI MELVLGKLAT TTTDTSSVPK FTHHQNNTIT LKRSLILSSR
730 740 750 760 770 780
HGIRRKLIKQ LGEHKRVYQC NICSKIFQNS SNLSRHVRSH GDKLFKCEEC AKLFSRKESL
790 800 810 820 830 840
KQHVSYKHSR NEVDGEYRYR CGTCEKTFRI ESALEFHNCR TDDKTFQCEM CFRFFSTNSN
850 860 870 880 890 900
LSKHKKKHGD KKFACEVCSK MFYRKDVMLD HQRRHLEGVR RVKREDLEAG GENLVRYKKE
910 920 930 940 950 960
PSGCPVCGKV FSCRSNMNKH LLTHGDKKYT CEICGRKFFR VDVLRDHIHV HFKDIALMDD
970 980 990 1000 1010 1020
HQREEFIGKI GISSEENDDN SDESADSEPH KYSCKRCQLT FGRGKEYLKH IMEVHKEKGY
1030 1040 1050 1060 1070 1080
GCSICNRRFA LKATYHAHMV IHRENLPDPN VQKYIHPCEI CGRIFNSIGN LERHKLIHTG
1090 1100 1110 1120 1130 1140
VKSHACEQCG KSFARKDMLK EHMRVHDNVR EYLCAECGKG MKTKHALRHH MKLHKGIKEY
1150 1160 1170 1180 1190 1200
ECKECHRRFA QKVNMLKHCK RHTGIKDFMC ELCGKTFSER NTMETHKLIH TVGKQWTCSV
1210 1220 1230 1240 1250 1260
CDKKYVTEYM LQKHVQLTHD KVEAQSCQLC GTKVSTRASM SRHMRRKHPE VLAVRIDDLD
1270 1280 1290 1300 1310 1320
HLPETTTIDA SSIGIVQPEL TLEQEDLAEG KHGKAAKRSH KRKQKPEEEA GAPVPEDATF
1330 1340 1350 1360 1370 1380
SEYSEKETEF TGSVGDETNS AVQSIQQVVV TLGDPNVTTP SSSVGLTNIT VTPITTAAAT
1390 1400 1410 1420 1430 1440
QFTNLQPVAV GHLTTPERQL QLDNSILTVT FDTVSGSAML HNRQNDVQIH PQPEASNPQS
1450 1460 1470 1480 1490 1500
VAHFINLTTL VNSITPLGSQ LSDQHPLTWR AVPQTDVLPP SQPQAPPQQA AQPQVQAEQQ
QQQMYSY
Protein Neighborhood
Domains & Features
5 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P57071-1-unknown | MPRRRP... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P57071-78-acetylation | AARPPG... | 78 | acetylation- | N-TAILS | Overall Laboratory | Lange_Huesgen_et_al-RBC | |||
| P57071-301-unknown | MAEDGS... | 301 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000444044 | |||
| P57071-301-unknown | MAEDGS... | 301 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000390245 | |||
| P57071-1270- | ASSIGI... | 1270 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
| P57071-1272- | SIGIVQ... | 1272 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...QMYSY | 1507 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|