TopFIND 4.0

P60201: Myelin proteolipid protein

General Information

Protein names
- Myelin proteolipid protein
- PLP
- Lipophilin
Gene names PLP1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P60201

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGLLECCARC LVGAPFASLV ATGLCFFGVA LFCGCGHEAL TGTEKLIETY FSKNYQDYEY 
        70         80         90        100        110        120 
LINVIHAFQY VIYGTASFFF LYGALLLAEG FYTTGAVRQI FGDYKTTICG KGLSATVTGG 
       130        140        150        160        170        180 
QKGRGSRGQH QAHSLERVCH CLGKWLGHPD KFVGITYALT VVWLLVFACS AVPVYIYFNT 
       190        200        210        220        230        240 
WTTCQSIAFP SKTSASIGSL CADARMYGVL PWNAFPGKVC GSNLLSICKT AEFQMTFHLF 
       250        260        270    
IAAFVGAAAT LVSLLTFMIA ATYNFAVLKL MGRGTKF

Isoforms

- Isoform DM-20 of Myelin proteolipid protein

Sequence View

        10         20         30         40         50         60 
MGLLECCARC LVGAPFASLV ATGLCFFGVA LFCGCGHEAL TGTEKLIETY FSKNYQDYEY 
        70         80         90        100        110        120 
LINVIHAFQY VIYGTASFFF LYGALLLAEG FYTTGAVRQI FGDYKTTICG KGLSATVTGG 
       130        140        150        160        170        180 
QKGRGSRGQH QAHSLERVCH CLGKWLGHPD KFVGITYALT VVWLLVFACS AVPVYIYFNT 
       190        200        210        220        230        240 
WTTCQSIAFP SKTSASIGSL CADARMYGVL PWNAFPGKVC GSNLLSICKT AEFQMTFHLF 
       250        260        270    
IAAFVGAAAT LVSLLTFMIA ATYNFAVLKL MGRGTKF



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P60201-1-unknown MGLLEC... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt82100
    P60201-2-unknown GLLECC... 2 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P60201-2-unknown GLLECC... 2 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt110805

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RGTKF 277 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...RGTKF 277 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt77718

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)