Q16854: Deoxyguanosine kinase, mitochondrial

General Information

Protein names	- Deoxyguanosine kinase, mitochondrial - dGK - 2.7.1.113
Gene names	DGUOK
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q16854

2 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Deoxyguanosine kinase, mitochondrial - Isoform 3 of Deoxyguanosine kinase, mitochondrial - Isoform 4 of Deoxyguanosine kinase, mitochondrial - Isoform 5 of Deoxyguanosine kinase, mitochondrial - Isoform 6 of Deoxyguanosine kinase, mitochondrial

Sequence View

        10         20         30         40         50         60
MAAGRLFLSR LRAPFSSMAK SPLEGVSSSR GLHAGRGPRR LSIEGNIAVG KSTFVKLLTK
        70         80         90        100        110        120
TYPEWHVATE PVATWQNIQA AGTQKACTAQ SLGNLLDMMY REPARWSYTF QTFSFLSRLK
       130        140        150        160        170        180
VQLEPFPEKL LQARKPVQIF ERSVYSDRYI FAKNLFENGS LSDIEWHIYQ DWHSFLLWEF
       190        200        210        220        230        240
ASRITLHGFI YLQASPQVCL KRLYQRAREE EKGIELAYLE QLHGQHEAWL IHKTTKLHFE
       250        260        270
ALMNIPVLVL DVNDDFSEEV TKQEDLMREV NTFVKNL         10         20         30         40         50         60
MAAGRLFLSR LRAPFSSMAK SPLEGVSSSR GLHAGRGPRR LSIEGNIAVG KSTFVKLLTK
        70         80         90        100        110        120
TYPEWHVATE PVATWQNIQA AGTQKACTAQ SLGNLLDMMY REPARWSYTF QTFSFLSRLK
       130        140        150        160        170        180
VQLEPFPEKL LQARKPVQIF ERSVYSDRYI FAKNLFENGS LSDIEWHIYQ DWHSFLLWEF
       190        200        210        220        230        240
ASRITLHGFI YLQASPQVCL KRLYQRAREE EKGIELAYLE QLHGQHEAWL IHKTTKLHFE
       250        260        270
ALMNIPVLVL DVNDDFSEEV TKQEDLMREV NTFVKNL         10         20         30         40         50         60
MAAGRLFLSR LRAPFSSMAK SPLEGVSSSR GLHAGRGPRR LSIEGNIAVG KSTFVKLLTK
        70         80         90        100        110        120
TYPEWHVATE PVATWQNIQA AGTQKACTAQ SLGNLLDMMY REPARWSYTF QTFSFLSRLK
       130        140        150        160        170        180
VQLEPFPEKL LQARKPVQIF ERSVYSDRYI FAKNLFENGS LSDIEWHIYQ DWHSFLLWEF
       190        200        210        220        230        240
ASRITLHGFI YLQASPQVCL KRLYQRAREE EKGIELAYLE QLHGQHEAWL IHKTTKLHFE
       250        260        270
ALMNIPVLVL DVNDDFSEEV TKQEDLMREV NTFVKNL         10         20         30         40         50         60
MAAGRLFLSR LRAPFSSMAK SPLEGVSSSR GLHAGRGPRR LSIEGNIAVG KSTFVKLLTK
        70         80         90        100        110        120
TYPEWHVATE PVATWQNIQA AGTQKACTAQ SLGNLLDMMY REPARWSYTF QTFSFLSRLK
       130        140        150        160        170        180
VQLEPFPEKL LQARKPVQIF ERSVYSDRYI FAKNLFENGS LSDIEWHIYQ DWHSFLLWEF
       190        200        210        220        230        240
ASRITLHGFI YLQASPQVCL KRLYQRAREE EKGIELAYLE QLHGQHEAWL IHKTTKLHFE
       250        260        270
ALMNIPVLVL DVNDDFSEEV TKQEDLMREV NTFVKNL         10         20         30         40         50         60
MAAGRLFLSR LRAPFSSMAK SPLEGVSSSR GLHAGRGPRR LSIEGNIAVG KSTFVKLLTK
        70         80         90        100        110        120
TYPEWHVATE PVATWQNIQA AGTQKACTAQ SLGNLLDMMY REPARWSYTF QTFSFLSRLK
       130        140        150        160        170        180
VQLEPFPEKL LQARKPVQIF ERSVYSDRYI FAKNLFENGS LSDIEWHIYQ DWHSFLLWEF
       190        200        210        220        230        240
ASRITLHGFI YLQASPQVCL KRLYQRAREE EKGIELAYLE QLHGQHEAWL IHKTTKLHFE
       250        260        270
ALMNIPVLVL DVNDDFSEEV TKQEDLMREV NTFVKNL

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q16854-1-unknown	MAAGRL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt72689
Q16854-1-unknown	MAAGRL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt72690
Q16854-1-unknown	MAAGRL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt72691
Q16854-1-unknown	MAAGRL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt72692
Q16854-40-unknown	RLSIEG...	40	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q16854-40-unknown	RLSIEG...	40	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt115406

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...FVKNL	277	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...FVKNL	277	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt68309
...FVKNL	277	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt68307
...FVKNL	277	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt68308
...FVKNL	277	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt68310
...FVKNL	277		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...FVKNL	277		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...FVKNL	277		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...FVKNL	277		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)