TopFIND 4.0

Q5QJU3: Alkaline ceramidase 2 {ECO:0000305}

General Information

Protein names
- Alkaline ceramidase 2 {ECO:0000305}
- AlkCDase 2
- Alkaline CDase 2
- haCER2
- 3.5.1.- {ECO:0000269|PubMed:20207939, ECO:0000269|PubMed:20628055}
- 3.5.1.23 {ECO:0000269|PubMed:16940153, ECO:0000269|PubMed:20089856, ECO:0000269|PubMed:20207939}
- Acylsphingosine deacylase 3-like
- N-acylsphingosine amidohydrolase 3-like
Gene names ACER2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q5QJU3

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGAPHWWDQL QAGSSEVDWC EDNYTIVPAI AEFYNTISNV LFFILPPICM CLFRQYATCF 
        70         80         90        100        110        120 
NSGIYLIWTL LVVVGIGSVY FHATLSFLGQ MLDELAVLWV LMCALAMWFP RRYLPKIFRN 
       130        140        150        160        170        180 
DRGRFKVVVS VLSAVTTCLA FVKPAINNIS LMTLGVPCTA LLIAELKRCD NMRVFKLGLF 
       190        200        210        220        230        240 
SGLWWTLALF CWISDRAFCE LLSSFNFPYL HCMWHILICL AAYLGCVCFA YFDAASEIPE 
       250        260        270    
QGPVIKFWPN EKWAFIGVPY VSLLCANKKS SVKIT

Isoforms

- Isoform 2 of Alkaline ceramidase 2 - Isoform 3 of Alkaline ceramidase 2

Sequence View

        10         20         30         40         50         60 
MGAPHWWDQL QAGSSEVDWC EDNYTIVPAI AEFYNTISNV LFFILPPICM CLFRQYATCF 
        70         80         90        100        110        120 
NSGIYLIWTL LVVVGIGSVY FHATLSFLGQ MLDELAVLWV LMCALAMWFP RRYLPKIFRN 
       130        140        150        160        170        180 
DRGRFKVVVS VLSAVTTCLA FVKPAINNIS LMTLGVPCTA LLIAELKRCD NMRVFKLGLF 
       190        200        210        220        230        240 
SGLWWTLALF CWISDRAFCE LLSSFNFPYL HCMWHILICL AAYLGCVCFA YFDAASEIPE 
       250        260        270    
QGPVIKFWPN EKWAFIGVPY VSLLCANKKS SVKIT         10         20         30         40         50         60 
MGAPHWWDQL QAGSSEVDWC EDNYTIVPAI AEFYNTISNV LFFILPPICM CLFRQYATCF 
        70         80         90        100        110        120 
NSGIYLIWTL LVVVGIGSVY FHATLSFLGQ MLDELAVLWV LMCALAMWFP RRYLPKIFRN 
       130        140        150        160        170        180 
DRGRFKVVVS VLSAVTTCLA FVKPAINNIS LMTLGVPCTA LLIAELKRCD NMRVFKLGLF 
       190        200        210        220        230        240 
SGLWWTLALF CWISDRAFCE LLSSFNFPYL HCMWHILICL AAYLGCVCFA YFDAASEIPE 
       250        260        270    
QGPVIKFWPN EKWAFIGVPY VSLLCANKKS SVKIT



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q5QJU3-1-unknown MGAPHW... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q5QJU3-50-unknown MCLFRQ... 50 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt66133
    Q5QJU3-50-unknown MCLFRQ... 50 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt66134

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SVKIT 275 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...SVKIT 275 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt61751

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)