Q5VWK5: Interleukin-23 receptor

General Information

Protein names	- Interleukin-23 receptor - IL-23 receptor - IL-23R
Gene names	IL23R
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q5VWK5

4 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Interleukin-23 receptor - Isoform 3 of Interleukin-23 receptor - Isoform 4 of Interleukin-23 receptor - Isoform 5 of Interleukin-23 receptor - Isoform 6 of Interleukin-23 receptor - Isoform 7 of Interleukin-23 receptor

Sequence View

        10         20         30         40         50         60
MNQVTIQWDA VIALYILFSW CHGGITNINC SGHIWVEPAT IFKMGMNISI YCQAAIKNCQ
        70         80         90        100        110        120
PRKLHFYKNG IKERFQITRI NKTTARLWYK NFLEPHASMY CTAECPKHFQ ETLICGKDIS
       130        140        150        160        170        180
SGYPPDIPDE VTCVIYEYSG NMTCTWNAGK LTYIDTKYVV HVKSLETEEE QQYLTSSYIN
       190        200        210        220        230        240
ISTDSLQGGK KYLVWVQAAN ALGMEESKQL QIHLDDIVIP SAAVISRAET INATVPKTII
       250        260        270        280        290        300
YWDSQTTIEK VSCEMRYKAT TNQTWNVKEF DTNFTYVQQS EFYLEPNIKY VFQVRCQETG
       310        320        330        340        350        360
KRYWQPWSSL FFHKTPETVP QVTSKAFQHD TWNSGLTVAS ISTGHLTSDN RGDIGLLLGM
       370        380        390        400        410        420
IVFAVMLSIL SLIGIFNRSF RTGIKRRILL LIPKWLYEDI PNMKNSNVVK MLQENSELMN
       430        440        450        460        470        480
NNSSEQVLYV DPMITEIKEI FIPEHKPTDY KKENTGPLET RDYPQNSLFD NTTVVYIPDL
       490        500        510        520        530        540
NTGYKPQISN FLPEGSHLSN NNEITSLTLK PPVDSLDSGN NPRLQKHPNF AFSVSSVNSL
       550        560        570        580        590        600
SNTIFLGELS LILNQGECSS PDIQNSVEEE TTMLLENDSP SETIPEQTLL PDEFVSCLGI
       610        620
VNEELPSINT YFPQNILESH FNRISLLEK         10         20         30         40         50         60
MNQVTIQWDA VIALYILFSW CHGGITNINC SGHIWVEPAT IFKMGMNISI YCQAAIKNCQ
        70         80         90        100        110        120
PRKLHFYKNG IKERFQITRI NKTTARLWYK NFLEPHASMY CTAECPKHFQ ETLICGKDIS
       130        140        150        160        170        180
SGYPPDIPDE VTCVIYEYSG NMTCTWNAGK LTYIDTKYVV HVKSLETEEE QQYLTSSYIN
       190        200        210        220        230        240
ISTDSLQGGK KYLVWVQAAN ALGMEESKQL QIHLDDIVIP SAAVISRAET INATVPKTII
       250        260        270        280        290        300
YWDSQTTIEK VSCEMRYKAT TNQTWNVKEF DTNFTYVQQS EFYLEPNIKY VFQVRCQETG
       310        320        330        340        350        360
KRYWQPWSSL FFHKTPETVP QVTSKAFQHD TWNSGLTVAS ISTGHLTSDN RGDIGLLLGM
       370        380        390        400        410        420
IVFAVMLSIL SLIGIFNRSF RTGIKRRILL LIPKWLYEDI PNMKNSNVVK MLQENSELMN
       430        440        450        460        470        480
NNSSEQVLYV DPMITEIKEI FIPEHKPTDY KKENTGPLET RDYPQNSLFD NTTVVYIPDL
       490        500        510        520        530        540
NTGYKPQISN FLPEGSHLSN NNEITSLTLK PPVDSLDSGN NPRLQKHPNF AFSVSSVNSL
       550        560        570        580        590        600
SNTIFLGELS LILNQGECSS PDIQNSVEEE TTMLLENDSP SETIPEQTLL PDEFVSCLGI
       610        620
VNEELPSINT YFPQNILESH FNRISLLEK         10         20         30         40         50         60
MNQVTIQWDA VIALYILFSW CHGGITNINC SGHIWVEPAT IFKMGMNISI YCQAAIKNCQ
        70         80         90        100        110        120
PRKLHFYKNG IKERFQITRI NKTTARLWYK NFLEPHASMY CTAECPKHFQ ETLICGKDIS
       130        140        150        160        170        180
SGYPPDIPDE VTCVIYEYSG NMTCTWNAGK LTYIDTKYVV HVKSLETEEE QQYLTSSYIN
       190        200        210        220        230        240
ISTDSLQGGK KYLVWVQAAN ALGMEESKQL QIHLDDIVIP SAAVISRAET INATVPKTII
       250        260        270        280        290        300
YWDSQTTIEK VSCEMRYKAT TNQTWNVKEF DTNFTYVQQS EFYLEPNIKY VFQVRCQETG
       310        320        330        340        350        360
KRYWQPWSSL FFHKTPETVP QVTSKAFQHD TWNSGLTVAS ISTGHLTSDN RGDIGLLLGM
       370        380        390        400        410        420
IVFAVMLSIL SLIGIFNRSF RTGIKRRILL LIPKWLYEDI PNMKNSNVVK MLQENSELMN
       430        440        450        460        470        480
NNSSEQVLYV DPMITEIKEI FIPEHKPTDY KKENTGPLET RDYPQNSLFD NTTVVYIPDL
       490        500        510        520        530        540
NTGYKPQISN FLPEGSHLSN NNEITSLTLK PPVDSLDSGN NPRLQKHPNF AFSVSSVNSL
       550        560        570        580        590        600
SNTIFLGELS LILNQGECSS PDIQNSVEEE TTMLLENDSP SETIPEQTLL PDEFVSCLGI
       610        620
VNEELPSINT YFPQNILESH FNRISLLEK         10         20         30         40         50         60
MNQVTIQWDA VIALYILFSW CHGGITNINC SGHIWVEPAT IFKMGMNISI YCQAAIKNCQ
        70         80         90        100        110        120
PRKLHFYKNG IKERFQITRI NKTTARLWYK NFLEPHASMY CTAECPKHFQ ETLICGKDIS
       130        140        150        160        170        180
SGYPPDIPDE VTCVIYEYSG NMTCTWNAGK LTYIDTKYVV HVKSLETEEE QQYLTSSYIN
       190        200        210        220        230        240
ISTDSLQGGK KYLVWVQAAN ALGMEESKQL QIHLDDIVIP SAAVISRAET INATVPKTII
       250        260        270        280        290        300
YWDSQTTIEK VSCEMRYKAT TNQTWNVKEF DTNFTYVQQS EFYLEPNIKY VFQVRCQETG
       310        320        330        340        350        360
KRYWQPWSSL FFHKTPETVP QVTSKAFQHD TWNSGLTVAS ISTGHLTSDN RGDIGLLLGM
       370        380        390        400        410        420
IVFAVMLSIL SLIGIFNRSF RTGIKRRILL LIPKWLYEDI PNMKNSNVVK MLQENSELMN
       430        440        450        460        470        480
NNSSEQVLYV DPMITEIKEI FIPEHKPTDY KKENTGPLET RDYPQNSLFD NTTVVYIPDL
       490        500        510        520        530        540
NTGYKPQISN FLPEGSHLSN NNEITSLTLK PPVDSLDSGN NPRLQKHPNF AFSVSSVNSL
       550        560        570        580        590        600
SNTIFLGELS LILNQGECSS PDIQNSVEEE TTMLLENDSP SETIPEQTLL PDEFVSCLGI
       610        620
VNEELPSINT YFPQNILESH FNRISLLEK         10         20         30         40         50         60
MNQVTIQWDA VIALYILFSW CHGGITNINC SGHIWVEPAT IFKMGMNISI YCQAAIKNCQ
        70         80         90        100        110        120
PRKLHFYKNG IKERFQITRI NKTTARLWYK NFLEPHASMY CTAECPKHFQ ETLICGKDIS
       130        140        150        160        170        180
SGYPPDIPDE VTCVIYEYSG NMTCTWNAGK LTYIDTKYVV HVKSLETEEE QQYLTSSYIN
       190        200        210        220        230        240
ISTDSLQGGK KYLVWVQAAN ALGMEESKQL QIHLDDIVIP SAAVISRAET INATVPKTII
       250        260        270        280        290        300
YWDSQTTIEK VSCEMRYKAT TNQTWNVKEF DTNFTYVQQS EFYLEPNIKY VFQVRCQETG
       310        320        330        340        350        360
KRYWQPWSSL FFHKTPETVP QVTSKAFQHD TWNSGLTVAS ISTGHLTSDN RGDIGLLLGM
       370        380        390        400        410        420
IVFAVMLSIL SLIGIFNRSF RTGIKRRILL LIPKWLYEDI PNMKNSNVVK MLQENSELMN
       430        440        450        460        470        480
NNSSEQVLYV DPMITEIKEI FIPEHKPTDY KKENTGPLET RDYPQNSLFD NTTVVYIPDL
       490        500        510        520        530        540
NTGYKPQISN FLPEGSHLSN NNEITSLTLK PPVDSLDSGN NPRLQKHPNF AFSVSSVNSL
       550        560        570        580        590        600
SNTIFLGELS LILNQGECSS PDIQNSVEEE TTMLLENDSP SETIPEQTLL PDEFVSCLGI
       610        620
VNEELPSINT YFPQNILESH FNRISLLEK         10         20         30         40         50         60
MNQVTIQWDA VIALYILFSW CHGGITNINC SGHIWVEPAT IFKMGMNISI YCQAAIKNCQ
        70         80         90        100        110        120
PRKLHFYKNG IKERFQITRI NKTTARLWYK NFLEPHASMY CTAECPKHFQ ETLICGKDIS
       130        140        150        160        170        180
SGYPPDIPDE VTCVIYEYSG NMTCTWNAGK LTYIDTKYVV HVKSLETEEE QQYLTSSYIN
       190        200        210        220        230        240
ISTDSLQGGK KYLVWVQAAN ALGMEESKQL QIHLDDIVIP SAAVISRAET INATVPKTII
       250        260        270        280        290        300
YWDSQTTIEK VSCEMRYKAT TNQTWNVKEF DTNFTYVQQS EFYLEPNIKY VFQVRCQETG
       310        320        330        340        350        360
KRYWQPWSSL FFHKTPETVP QVTSKAFQHD TWNSGLTVAS ISTGHLTSDN RGDIGLLLGM
       370        380        390        400        410        420
IVFAVMLSIL SLIGIFNRSF RTGIKRRILL LIPKWLYEDI PNMKNSNVVK MLQENSELMN
       430        440        450        460        470        480
NNSSEQVLYV DPMITEIKEI FIPEHKPTDY KKENTGPLET RDYPQNSLFD NTTVVYIPDL
       490        500        510        520        530        540
NTGYKPQISN FLPEGSHLSN NNEITSLTLK PPVDSLDSGN NPRLQKHPNF AFSVSSVNSL
       550        560        570        580        590        600
SNTIFLGELS LILNQGECSS PDIQNSVEEE TTMLLENDSP SETIPEQTLL PDEFVSCLGI
       610        620
VNEELPSINT YFPQNILESH FNRISLLEK

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q5VWK5-1-unknown	MNQVTI...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt77744
Q5VWK5-1-unknown	MNQVTI...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt77745
Q5VWK5-24-unknown	GITNIN...	24	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q5VWK5-24-unknown	GITNIN...	24	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113495
Q5VWK5-24-unknown	GITNIN...	24	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113496
Q5VWK5-255-unknown	MRYKAT...	255	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt77743
Q5VWK5-255-unknown	MRYKAT...	255	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt105655
Q5VWK5-403-unknown	MKNSNV...	403	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt77748
Q5VWK5-403-unknown	MKNSNV...	403	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt105953
Q5VWK5-403-unknown	MKNSNV...	403	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt105952
Q5VWK5-403-unknown	MKNSNV...	403	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt105954

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SLLEK	629	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...SLLEK	629	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt73366
...SLLEK	629	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt73364
...SLLEK	629	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt73365
...SLLEK	629	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt73361

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)