TopFIND 4.0

Q60806: Serine/threonine-protein kinase PLK3

General Information

Protein names
- Serine/threonine-protein kinase PLK3
- 2.7.11.21
- Cytokine-inducible serine/threonine-protein kinase
- FGF-inducible kinase
- Polo-like kinase 3
- PLK-3
Gene names Plk3
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q60806

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEPAAGFLSP RPFPRAAVPS APPAGPGPPA NASPRSEPEV LAGPRAPDPP GRLITDPLSG 
        70         80         90        100        110        120 
RTYTKGRLLG KGGFARCYEA TDTESGIAYA VKVIPQSRVA KPHQREKILN EIELHRDLQH 
       130        140        150        160        170        180 
RHIVRFSHHF EDADNIYIFL ELCSRKSLAH IWKARHTLLE PEVRYYLRQI LSGLKYLHQR 
       190        200        210        220        230        240 
GILHRDLKLG NFFITDNMEL KVGDFGLAAR LEPPEQRKKT ICGTPNYVAP EVLLRQGHGP 
       250        260        270        280        290        300 
EADVWSLGCV MYTLLCGSPP FETADLKETY RCIKQVHYTL PASLSLPARQ LLAAILRASP 
       310        320        330        340        350        360 
RDRPSIEQIL RHDFFTKGYT PDRLPVSSCV TVPDLTPPNP ARSLFAKVTK SLFGRKKNKN 
       370        380        390        400        410        420 
KNHSEDQDNV SCLAPVVSGQ APASLIETAA EDSSPRGTLA SSGDGFEEGL TVATVVESAL 
       430        440        450        460        470        480 
CALRNCVAFM PPAEQNPAPL AQPEPLVWVS KWVDYSNKFG FGYQLSSRRV AVLFNDGTHM 
       490        500        510        520        530        540 
ALSANRKTVH YNPTSTKHFS FSMGSVPRAL QPQLGILRYF ASYMEQHLMK GGDLPSVEEA 
       550        560        570        580        590        600 
EVPAPPLLLQ WVKTDQALLM LFSDGTVQVN FYGDHTKLIL SGWEPLLVTF VARNRSACTY 
       610        620        630    
LASHLRQLGC SPDLRQRLRY ALRLLRDQSP A

Isoforms

- Isoform 2 of Serine/threonine-protein kinase PLK3

Sequence View

        10         20         30         40         50         60 
MEPAAGFLSP RPFPRAAVPS APPAGPGPPA NASPRSEPEV LAGPRAPDPP GRLITDPLSG 
        70         80         90        100        110        120 
RTYTKGRLLG KGGFARCYEA TDTESGIAYA VKVIPQSRVA KPHQREKILN EIELHRDLQH 
       130        140        150        160        170        180 
RHIVRFSHHF EDADNIYIFL ELCSRKSLAH IWKARHTLLE PEVRYYLRQI LSGLKYLHQR 
       190        200        210        220        230        240 
GILHRDLKLG NFFITDNMEL KVGDFGLAAR LEPPEQRKKT ICGTPNYVAP EVLLRQGHGP 
       250        260        270        280        290        300 
EADVWSLGCV MYTLLCGSPP FETADLKETY RCIKQVHYTL PASLSLPARQ LLAAILRASP 
       310        320        330        340        350        360 
RDRPSIEQIL RHDFFTKGYT PDRLPVSSCV TVPDLTPPNP ARSLFAKVTK SLFGRKKNKN 
       370        380        390        400        410        420 
KNHSEDQDNV SCLAPVVSGQ APASLIETAA EDSSPRGTLA SSGDGFEEGL TVATVVESAL 
       430        440        450        460        470        480 
CALRNCVAFM PPAEQNPAPL AQPEPLVWVS KWVDYSNKFG FGYQLSSRRV AVLFNDGTHM 
       490        500        510        520        530        540 
ALSANRKTVH YNPTSTKHFS FSMGSVPRAL QPQLGILRYF ASYMEQHLMK GGDLPSVEEA 
       550        560        570        580        590        600 
EVPAPPLLLQ WVKTDQALLM LFSDGTVQVN FYGDHTKLIL SGWEPLLVTF VARNRSACTY 
       610        620        630    
LASHLRQLGC SPDLRQRLRY ALRLLRDQSP A



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q60806-1-unknown MEPAAG... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q60806-1-unknown MEPAAG... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt85574

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...DQSPA 631 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...DQSPA 631 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt81192

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)