TopFIND 4.0

Q69ZA1: Cyclin-dependent kinase 13

General Information

Protein names
- Cyclin-dependent kinase 13
- 2.7.11.22
- 2.7.11.23
- CDC2-related protein kinase 5
- Cell division cycle 2-like protein kinase 5
- Cell division protein kinase 13
Gene names Cdk13
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q69ZA1

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPSSSDTALG GGGGLSWAEK KLEERRKRRR FLSPQQPPLL LPLLQPQLLQ PPPPPPPLLF 
        70         80         90        100        110        120 
LAAPGAAAAA AAAAAASSSC FSPGPPLEVK RLARGKRRPG GRQKRRRGPR AGQEAEKRRV 
       130        140        150        160        170        180 
FSLPQPQQDG GGGASSGGGV TPLVEYEDVS SQSEQGLLLG GASAATAATA AGGTGGNGGS 
       190        200        210        220        230        240 
PASSSGTQRR AEGSERRPRR DRRSSSGRSK ERHREHRRRD GTRSGSEASK ARSRHGHSGE 
       250        260        270        280        290        300 
ERAEAAKSGS SSSSGGRRKS ASATSSSSSS RKDRDLKAHR SRTKSSKEPP SAYKEPPKAY 
       310        320        330        340        350        360 
REDKSEPKAY RRRQRSLSPL GGRDESPVSH RASQSLRSRK SPSPAGGGSS PYSRRLPRSP 
       370        380        390        400        410        420 
SPYSRRRSPS YSRHSSYERG GDVSPSPYSS SSWRRSRSPY SPVLRRSAKS RSRSPYSSRH 
       430        440        450        460        470        480 
SRSRSRHRLS RSRSRHSSIS PSTLTLKSSL AAELNKNKKA RAAEAARAAE AAKAAEAAKA 
       490        500        510        520        530        540 
AEAAAKAAKA SNASTPTKGN TETGASVSQT NHVKEVKKLK TEHAPSPSSG GTVKSDKAKT 
       550        560        570        580        590        600 
KPPLQVTKVD NNLTVEKATK KTVVGKESKP AATKEEPVST KEKSKPLTPS TGAKEKEQHV 
       610        620        630        640        650        660 
ALVTSTLPPL PLPPMLPEDK DADSLRGNIS VKAVKKEVEK KLRCLLADLP LPPELPGGDD 
       670        680        690        700        710        720 
LSKSPEEKKT AAQLHSKRRP KICGPRYGEI KEKDIDWGKR CVDKFDIIGI IGEGTYGQVY 
       730        740        750        760        770        780 
KARDKDTGEM VALKKVRLDN EKEGFPITAI REIKILRQLT HQSIINMKEI VTDKEDALDF 
       790        800        810        820        830        840 
KKDKGAFYLV FEYMDHDLMG LLESGLVHFN ENHIKSFMRQ LMEGLDYCHK KNFLHRDIKC 
       850        860        870        880        890        900 
SNILLNNRGQ IKLADFGLAR LYSSEESRPY TNKVITLWYR PPELLLGEER YTPAIDVWSC 
       910        920        930        940        950        960 
GCILGELFTK KPIFQANQEL AQLELISRIC GSPCPAVWPD VIKLPYFNTM KPKKQYRRKL 
       970        980        990       1000       1010       1020 
REEFVFIPAA ALDLFDYMLA LDPSKRCTAE QALQCEFLRD VEPSKMPPPD LPLWQDCHEL 
      1030       1040       1050       1060       1070       1080 
WSKKRRRQKQ MGMTDDLSTI KAPRKDLSLG LDDSRTNTPQ GVLPPAQLKS QSNSNVAPVI 
      1090       1100       1110       1120       1130       1140 
TGPGQPLNHS ELAILLNLLQ SKSSVNMADF VQVLNIKVNS ETQQQLNKIN LPAGILATGE 
      1150       1160       1170       1180       1190       1200 
KQTDPSTPQQ ESSKSLGGVQ PSQTIQPKVE TDAAQAAVQS AFAVLLTQLI KAQQSKQKDA 
      1210       1220       1230       1240       1250       1260 
MLEERENGSG HEAPLQLRPP LEPSTPGSGQ DDLIQHQDRR ILELTPEPDR PRILPPDQRP 
      1270       1280       1290       1300       1310       1320 
PEPPEPPPVT EEDLDYRTEN QHVPTTSSSL TDPHAGVKAA LLQLLAQHQP QDDPKREGGI 
      1330       1340       1350       1360       1370       1380 
DYPTGDTYVP SSDYKDNFGS SFSAAPYVSS DGLGSSSAAA PLEARSFIGN SDIQSLDNYS 
      1390       1400       1410       1420       1430       1440 
TASSHTGGPP QTSAFTESFA SSVAGYGDIY LNAGPMLFSG DKDHRFEYSH GPITVLTNSN 
      1450       1460       1470       1480       1490       1500 
DPSTGPESTH PLPAKMHNYN YGGNLQENPG GPSLMHGQTW TSPAQGPGYS QGYRGHISTS 
      1510    
AGRGRGRGLP Y

Isoforms

- Isoform 2 of Cyclin-dependent kinase 13

Sequence View

        10         20         30         40         50         60 
MPSSSDTALG GGGGLSWAEK KLEERRKRRR FLSPQQPPLL LPLLQPQLLQ PPPPPPPLLF 
        70         80         90        100        110        120 
LAAPGAAAAA AAAAAASSSC FSPGPPLEVK RLARGKRRPG GRQKRRRGPR AGQEAEKRRV 
       130        140        150        160        170        180 
FSLPQPQQDG GGGASSGGGV TPLVEYEDVS SQSEQGLLLG GASAATAATA AGGTGGNGGS 
       190        200        210        220        230        240 
PASSSGTQRR AEGSERRPRR DRRSSSGRSK ERHREHRRRD GTRSGSEASK ARSRHGHSGE 
       250        260        270        280        290        300 
ERAEAAKSGS SSSSGGRRKS ASATSSSSSS RKDRDLKAHR SRTKSSKEPP SAYKEPPKAY 
       310        320        330        340        350        360 
REDKSEPKAY RRRQRSLSPL GGRDESPVSH RASQSLRSRK SPSPAGGGSS PYSRRLPRSP 
       370        380        390        400        410        420 
SPYSRRRSPS YSRHSSYERG GDVSPSPYSS SSWRRSRSPY SPVLRRSAKS RSRSPYSSRH 
       430        440        450        460        470        480 
SRSRSRHRLS RSRSRHSSIS PSTLTLKSSL AAELNKNKKA RAAEAARAAE AAKAAEAAKA 
       490        500        510        520        530        540 
AEAAAKAAKA SNASTPTKGN TETGASVSQT NHVKEVKKLK TEHAPSPSSG GTVKSDKAKT 
       550        560        570        580        590        600 
KPPLQVTKVD NNLTVEKATK KTVVGKESKP AATKEEPVST KEKSKPLTPS TGAKEKEQHV 
       610        620        630        640        650        660 
ALVTSTLPPL PLPPMLPEDK DADSLRGNIS VKAVKKEVEK KLRCLLADLP LPPELPGGDD 
       670        680        690        700        710        720 
LSKSPEEKKT AAQLHSKRRP KICGPRYGEI KEKDIDWGKR CVDKFDIIGI IGEGTYGQVY 
       730        740        750        760        770        780 
KARDKDTGEM VALKKVRLDN EKEGFPITAI REIKILRQLT HQSIINMKEI VTDKEDALDF 
       790        800        810        820        830        840 
KKDKGAFYLV FEYMDHDLMG LLESGLVHFN ENHIKSFMRQ LMEGLDYCHK KNFLHRDIKC 
       850        860        870        880        890        900 
SNILLNNRGQ IKLADFGLAR LYSSEESRPY TNKVITLWYR PPELLLGEER YTPAIDVWSC 
       910        920        930        940        950        960 
GCILGELFTK KPIFQANQEL AQLELISRIC GSPCPAVWPD VIKLPYFNTM KPKKQYRRKL 
       970        980        990       1000       1010       1020 
REEFVFIPAA ALDLFDYMLA LDPSKRCTAE QALQCEFLRD VEPSKMPPPD LPLWQDCHEL 
      1030       1040       1050       1060       1070       1080 
WSKKRRRQKQ MGMTDDLSTI KAPRKDLSLG LDDSRTNTPQ GVLPPAQLKS QSNSNVAPVI 
      1090       1100       1110       1120       1130       1140 
TGPGQPLNHS ELAILLNLLQ SKSSVNMADF VQVLNIKVNS ETQQQLNKIN LPAGILATGE 
      1150       1160       1170       1180       1190       1200 
KQTDPSTPQQ ESSKSLGGVQ PSQTIQPKVE TDAAQAAVQS AFAVLLTQLI KAQQSKQKDA 
      1210       1220       1230       1240       1250       1260 
MLEERENGSG HEAPLQLRPP LEPSTPGSGQ DDLIQHQDRR ILELTPEPDR PRILPPDQRP 
      1270       1280       1290       1300       1310       1320 
PEPPEPPPVT EEDLDYRTEN QHVPTTSSSL TDPHAGVKAA LLQLLAQHQP QDDPKREGGI 
      1330       1340       1350       1360       1370       1380 
DYPTGDTYVP SSDYKDNFGS SFSAAPYVSS DGLGSSSAAA PLEARSFIGN SDIQSLDNYS 
      1390       1400       1410       1420       1430       1440 
TASSHTGGPP QTSAFTESFA SSVAGYGDIY LNAGPMLFSG DKDHRFEYSH GPITVLTNSN 
      1450       1460       1470       1480       1490       1500 
DPSTGPESTH PLPAKMHNYN YGGNLQENPG GPSLMHGQTW TSPAQGPGYS QGYRGHISTS 
      1510    
AGRGRGRGLP Y



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q69ZA1-1-unknown MPSSSD... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q69ZA1-1-unknown MPSSSD... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt70083

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RGLPY 1511 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...RGLPY 1511 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt65701

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)