Q6ZMR5: Transmembrane protease serine 11A

General Information

Protein names	- Transmembrane protease serine 11A - 3.4.21.- - Airway trypsin-like protease 1 - Epidermal type-II transmembrane serine protease - Esophageal cancer-susceptibility gene 1 protein
Gene names	TMPRSS11A
Organism	Homo sapiens
Protease Family
Protease ID	S01.292
Chromosome location
UniProt ID	Q6ZMR5

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MMYRTVGFGT RSRNLKPWMI AVLIVLSLTV VAVTIGLLVH FLVFDQKKEY YHGSFKILDP
        70         80         90        100        110        120
QINNNFGQSN TYQLKDLRET TENLVSQVDE IFIDSAWKKN YIKNQVVRLT PEEDGVKVDV
       130        140        150        160        170        180
IMVFQFPSTE QRAVREKKIQ SILNQKIRNL RALPINASSV QVNAMSSSTG ELTVQASCGK
       190        200        210        220        230        240
RVVPLNVNRI ASGVIAPKAA WPWQASLQYD NIHQCGATLI SNTWLVTAAH CFQKYKNPHQ
       250        260        270        280        290        300
WTVSFGTKIN PPLMKRNVRR FIIHEKYRSA AREYDIAVVQ VSSRVTFSDD IRRICLPEAS
       310        320        330        340        350        360
ASFQPNLTVH ITGFGALYYG GESQNDLREA RVKIISDDVC KQPQVYGNDI KPGMFCAGYM
       370        380        390        400        410        420
EGIYDACRGD SGGPLVTRDL KDTWYLIGIV SWGDNCGQKD KPGVYTQVTY YRNWIASKTG

I

Isoforms

- Isoform 2 of Transmembrane protease serine 11A

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q6ZMR5-1-unknown	MMYRTV...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q6ZMR5-1-unknown	MMYRTV...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92287
Q6ZMR5-2-unknown	MYRTVG...	2	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000426911
Q6ZMR5-2-unknown	MYRTVG...	2	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt131376
Q6ZMR5-7-unknown	GFGTRS...	7	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000427621
Q6ZMR5-7-unknown	GFGTRS...	7	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt131378

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...SKTGI	421	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...SKTGI	421	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt87905

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)