TopFIND 4.0

Q6ZN66: Guanylate-binding protein 6

General Information

Protein names
- Guanylate-binding protein 6
- GTP-binding protein 6
- GBP-6
- Guanine nucleotide-binding protein 6
Gene names GBP6
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q6ZN66

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MESGPKMLAP VCLVENNNEQ LLVNQQAIQI LEKISQPVVV VAIVGLYRTG KSYLMNHLAG 
        70         80         90        100        110        120 
QNHGFPLGST VQSETKGIWM WCVPHPSKPN HTLVLLDTEG LGDVEKGDPK NDSWIFALAV 
       130        140        150        160        170        180 
LLCSTFVYNS MSTINHQALE QLHYVTELTE LIKAKSSPRP DGVEDSTEFV SFFPDFLWTV 
       190        200        210        220        230        240 
RDFTLELKLN GHPITEDEYL ENALKLIQGN NPRVQTSNFP RECIRRFFPK RKCFVFDRPT 
       250        260        270        280        290        300 
NDKDLLANIE KVSEKQLDPK FQEQTNIFCS YIFTHARTKT LREGITVTGN RLGTLAVTYV 
       310        320        330        340        350        360 
EAINSGAVPC LENAVITLAQ RENSAAVQRA ADYYSQQMAQ RVKLPTDTLQ ELLDMHAACE 
       370        380        390        400        410        420 
REAIAIFMEH SFKDENQEFQ KKFMETTMNK KGDFLLQNEE SSVQYCQAKL NELSKGLMES 
       430        440        450        460        470        480 
ISAGSFSVPG GHKLYMETKE RIEQDYWQVP RKGVKAKEVF QRFLESQMVI EESILQSDKA 
       490        500        510        520        530        540 
LTDREKAVAV DRAKKEAAEK EQELLKQKLQ EQQQQMEAQD KSRKENIAQL KEKLQMEREH 
       550        560        570        580        590        600 
LLREQIMMLE HTQKVQNDWL HEGFKKKYEE MNAEISQFKR MIDTTKNDDT PWIARTLDNL 
       610        620        630    
ADELTAILSA PAKLIGHGVK GVSSLFKKHK LPF

Isoforms

- Isoform 2 of Guanylate-binding protein 6

Sequence View

        10         20         30         40         50         60 
MESGPKMLAP VCLVENNNEQ LLVNQQAIQI LEKISQPVVV VAIVGLYRTG KSYLMNHLAG 
        70         80         90        100        110        120 
QNHGFPLGST VQSETKGIWM WCVPHPSKPN HTLVLLDTEG LGDVEKGDPK NDSWIFALAV 
       130        140        150        160        170        180 
LLCSTFVYNS MSTINHQALE QLHYVTELTE LIKAKSSPRP DGVEDSTEFV SFFPDFLWTV 
       190        200        210        220        230        240 
RDFTLELKLN GHPITEDEYL ENALKLIQGN NPRVQTSNFP RECIRRFFPK RKCFVFDRPT 
       250        260        270        280        290        300 
NDKDLLANIE KVSEKQLDPK FQEQTNIFCS YIFTHARTKT LREGITVTGN RLGTLAVTYV 
       310        320        330        340        350        360 
EAINSGAVPC LENAVITLAQ RENSAAVQRA ADYYSQQMAQ RVKLPTDTLQ ELLDMHAACE 
       370        380        390        400        410        420 
REAIAIFMEH SFKDENQEFQ KKFMETTMNK KGDFLLQNEE SSVQYCQAKL NELSKGLMES 
       430        440        450        460        470        480 
ISAGSFSVPG GHKLYMETKE RIEQDYWQVP RKGVKAKEVF QRFLESQMVI EESILQSDKA 
       490        500        510        520        530        540 
LTDREKAVAV DRAKKEAAEK EQELLKQKLQ EQQQQMEAQD KSRKENIAQL KEKLQMEREH 
       550        560        570        580        590        600 
LLREQIMMLE HTQKVQNDWL HEGFKKKYEE MNAEISQFKR MIDTTKNDDT PWIARTLDNL 
       610        620        630    
ADELTAILSA PAKLIGHGVK GVSSLFKKHK LPF



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q6ZN66-1-unknown MESGPK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q6ZN66-338-unknown MAQRVK... 338 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt75761

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...HKLPF 633 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...HKLPF 633 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt71379

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)