TopFIND 4.0

Q80WM7: Serine protease 33

General Information

Protein names
- Serine protease 33
- 3.4.21.-
- Tryptase-6
- mT6
Gene names Prss33
Organism Mus musculus
Protease Family
Protease ID S01.075
Chromosome location
UniProt ID Q80WM7

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRGASHLQIL LLLVLGTRMQ ECAACGQPRM SSRIVGGRDA QDGEWPWQTS IQHRGAHVCG 
        70         80         90        100        110        120 
GSLIAPQWVL TAGHCFPRRV WPSEYSVLLG ALSLDVRSSH ELLVPVLRVL LPPDYSEDEA 
       130        140        150        160        170        180 
RGDLALLQLR HPVSLSTRIQ PVCLPAPGSH PPPGSPCWVT GWGSLSPGVP LPKGRPLQGV 
       190        200        210        220        230        240 
RVPLLDSRAC DRLYHVGANV PQGERIVLPG NLCAGYRRGH KDACQGDSGG PLTCMESGHW 
       250        260        270    
VLVGVVSWGK GCALPNRPGV YTNVAKYSPW IQARLSL

Isoforms

- Isoform 2 of Serine protease 33

Sequence View

        10         20         30         40         50         60 
MRGASHLQIL LLLVLGTRMQ ECAACGQPRM SSRIVGGRDA QDGEWPWQTS IQHRGAHVCG 
        70         80         90        100        110        120 
GSLIAPQWVL TAGHCFPRRV WPSEYSVLLG ALSLDVRSSH ELLVPVLRVL LPPDYSEDEA 
       130        140        150        160        170        180 
RGDLALLQLR HPVSLSTRIQ PVCLPAPGSH PPPGSPCWVT GWGSLSPGVP LPKGRPLQGV 
       190        200        210        220        230        240 
RVPLLDSRAC DRLYHVGANV PQGERIVLPG NLCAGYRRGH KDACQGDSGG PLTCMESGHW 
       250        260        270    
VLVGVVSWGK GCALPNRPGV YTNVAKYSPW IQARLSL



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q80WM7-19-unknown MQECAA... 19 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt86312
    Q80WM7-25-unknown CGQPRM... 25 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q80WM7-25-unknown CGQPRM... 25 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt113844

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ARLSL 277 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...ARLSL 277 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt81930

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)