TopFIND 4.0

Q8NAN2: Mitoguardin 1 {ECO:0000303|PubMed:26711011}

General Information

Protein names
- Mitoguardin 1 {ECO:0000303|PubMed:26711011}
- Protein FAM73A {ECO:0000305}
Gene names FAM73A
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8NAN2

4

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSDCCSAPGI SWEAGVGRPA VPGLELQIRR GAMSEETVSE SQFSLKTAAL RVFDLPLTWY 
        70         80         90        100        110        120 
YSLSQIKFSP VAKKLFVVTA VSAISVIFLA HHFKRKRGKK KGKILPWEPE HLILEYTKRA 
       130        140        150        160        170        180 
ASDKGSSCSS SRQNLTLSLS STKDKGSQVC NYANGGLFSK YSGSAQSLAS VQSVNSCHSC 
       190        200        210        220        230        240 
ACGNSNSWDK ADEDDIKLVN IPVTTPENLY LMGMELFEEA LRRWEQALTF RNRQAEDEAC 
       250        260        270        280        290        300 
GSIKLGAGDA IAEENVDDII STEFIHKLEA LLQRAYRLQE EFEATLGASD PNSLADDIDK 
       310        320        330        340        350        360 
DTDITMKGNV EDFGLRDTLS IASTDSFASA AELAEHREVR HTYSLESLCH CPFYEEAMHL 
       370        380        390        400        410        420 
VEEGKIYSRV LRTEMLECLG DSDFLAKLHC IRQAFQVILS ESANRIFLAE SGRKILSALI 
       430        440        450        460        470        480 
VKARKNPKKF EDVFDEMIYF LEQTDHWGST EMELAARGVK NLNFYDVVLD FILMDSFEDL 
       490        500        510        520        530        540 
ENPPTSIQNV VNNRWLNSSF KETAVASSCW SVLKQKRQQM KIPDGFFAHF YAICEHISPV 
       550        560        570        580        590        600 
LAWGFLGPRN SLYDLCCFFK NQVLLFLKDI FDFEKVRYSS TETLAEDLMQ LLIRRTELLM 
       610        620        630    
AYLEADALRH TSSCLSSHGH VMSTGLLEAK VQ

Isoforms

- Isoform 2 of Protein FAM73A - Isoform 2 of Mitoguardin 1

Sequence View

        10         20         30         40         50         60 
MSDCCSAPGI SWEAGVGRPA VPGLELQIRR GAMSEETVSE SQFSLKTAAL RVFDLPLTWY 
        70         80         90        100        110        120 
YSLSQIKFSP VAKKLFVVTA VSAISVIFLA HHFKRKRGKK KGKILPWEPE HLILEYTKRA 
       130        140        150        160        170        180 
ASDKGSSCSS SRQNLTLSLS STKDKGSQVC NYANGGLFSK YSGSAQSLAS VQSVNSCHSC 
       190        200        210        220        230        240 
ACGNSNSWDK ADEDDIKLVN IPVTTPENLY LMGMELFEEA LRRWEQALTF RNRQAEDEAC 
       250        260        270        280        290        300 
GSIKLGAGDA IAEENVDDII STEFIHKLEA LLQRAYRLQE EFEATLGASD PNSLADDIDK 
       310        320        330        340        350        360 
DTDITMKGNV EDFGLRDTLS IASTDSFASA AELAEHREVR HTYSLESLCH CPFYEEAMHL 
       370        380        390        400        410        420 
VEEGKIYSRV LRTEMLECLG DSDFLAKLHC IRQAFQVILS ESANRIFLAE SGRKILSALI 
       430        440        450        460        470        480 
VKARKNPKKF EDVFDEMIYF LEQTDHWGST EMELAARGVK NLNFYDVVLD FILMDSFEDL 
       490        500        510        520        530        540 
ENPPTSIQNV VNNRWLNSSF KETAVASSCW SVLKQKRQQM KIPDGFFAHF YAICEHISPV 
       550        560        570        580        590        600 
LAWGFLGPRN SLYDLCCFFK NQVLLFLKDI FDFEKVRYSS TETLAEDLMQ LLIRRTELLM 
       610        620        630    
AYLEADALRH TSSCLSSHGH VMSTGLLEAK VQ         10         20         30         40         50         60 
MSDCCSAPGI SWEAGVGRPA VPGLELQIRR GAMSEETVSE SQFSLKTAAL RVFDLPLTWY 
        70         80         90        100        110        120 
YSLSQIKFSP VAKKLFVVTA VSAISVIFLA HHFKRKRGKK KGKILPWEPE HLILEYTKRA 
       130        140        150        160        170        180 
ASDKGSSCSS SRQNLTLSLS STKDKGSQVC NYANGGLFSK YSGSAQSLAS VQSVNSCHSC 
       190        200        210        220        230        240 
ACGNSNSWDK ADEDDIKLVN IPVTTPENLY LMGMELFEEA LRRWEQALTF RNRQAEDEAC 
       250        260        270        280        290        300 
GSIKLGAGDA IAEENVDDII STEFIHKLEA LLQRAYRLQE EFEATLGASD PNSLADDIDK 
       310        320        330        340        350        360 
DTDITMKGNV EDFGLRDTLS IASTDSFASA AELAEHREVR HTYSLESLCH CPFYEEAMHL 
       370        380        390        400        410        420 
VEEGKIYSRV LRTEMLECLG DSDFLAKLHC IRQAFQVILS ESANRIFLAE SGRKILSALI 
       430        440        450        460        470        480 
VKARKNPKKF EDVFDEMIYF LEQTDHWGST EMELAARGVK NLNFYDVVLD FILMDSFEDL 
       490        500        510        520        530        540 
ENPPTSIQNV VNNRWLNSSF KETAVASSCW SVLKQKRQQM KIPDGFFAHF YAICEHISPV 
       550        560        570        580        590        600 
LAWGFLGPRN SLYDLCCFFK NQVLLFLKDI FDFEKVRYSS TETLAEDLMQ LLIRRTELLM 
       610        620        630    
AYLEADALRH TSSCLSSHGH VMSTGLLEAK VQ



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Evidence Names:


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Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...EAKVQ 632 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)