TopFIND 4.0

Q8TCQ1: E3 ubiquitin-protein ligase MARCH1

General Information

Protein names
- E3 ubiquitin-protein ligase MARCH1
- 2.3.2.27
- Membrane-associated RING finger protein 1
- Membrane-associated RING-CH protein I
- MARCH-I
- RING finger protein 171
- RING-type E3 ubiquitin transferase MARCH1 {ECO:0000305}
Gene names MARCH1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8TCQ1

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MLGWCEAIAR NPHRIPNNTR TPEISGDLAD ASQTSTLNEK SPGRSASRSS NISKASSPTT 
        70         80         90        100        110        120 
GTAPRSQSRL SVCPSTQDIC RICHCEGDEE SPLITPCRCT GTLRFVHQSC LHQWIKSSDT 
       130        140        150        160        170        180 
RCCELCKYDF IMETKLKPLR KWEKLQMTTS ERRKIFCSVT FHVIAITCVV WSLYVLIDRT 
       190        200        210        220        230        240 
AEEIKQGNDN GVLEWPFWTK LVVVAIGFTG GLVFMYVQCK VYVQLWRRLK AYNRVIFVQN 
       250        260        270        280    
CPDTAKKLEK NFSCNVNTDI KDAVVVPVPQ TGANSLPSAE GGPPEVVSV

Isoforms

- Isoform 2 of E3 ubiquitin-protein ligase MARCH1

Sequence View

        10         20         30         40         50         60 
MLGWCEAIAR NPHRIPNNTR TPEISGDLAD ASQTSTLNEK SPGRSASRSS NISKASSPTT 
        70         80         90        100        110        120 
GTAPRSQSRL SVCPSTQDIC RICHCEGDEE SPLITPCRCT GTLRFVHQSC LHQWIKSSDT 
       130        140        150        160        170        180 
RCCELCKYDF IMETKLKPLR KWEKLQMTTS ERRKIFCSVT FHVIAITCVV WSLYVLIDRT 
       190        200        210        220        230        240 
AEEIKQGNDN GVLEWPFWTK LVVVAIGFTG GLVFMYVQCK VYVQLWRRLK AYNRVIFVQN 
       250        260        270        280    
CPDTAKKLEK NFSCNVNTDI KDAVVVPVPQ TGANSLPSAE GGPPEVVSV



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8TCQ1-1-unknown MLGWCE... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...EVVSV 289 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...EVVSV 289 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt76027

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)