TopFIND 4.0

Q8VD53: Alkaline ceramidase 2 {ECO:0000305}

General Information

Protein names
- Alkaline ceramidase 2 {ECO:0000305}
- AlkCDase 2
- Alkaline CDase 2
- maCER2
- 3.5.1.- {ECO:0000269|PubMed:29401619}
- 3.5.1.23 {ECO:0000269|PubMed:29401619}
- Acylsphingosine deacylase 3-like
- Cancer-related gene liver 1 protein
- CRG-L1
- N-acylsphingosine amidohydrolase 3-like
Gene names Acer2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8VD53

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGAPHWWDHL RAGSSEVDWC EDNYTIVPAI AEFYNTISNV LFFILPPICM CLFRQYATCF 
        70         80         90        100        110        120 
NSGIYLIWTL LVVVGIGSVY FHATLSFLGQ MLDELAILWV LMCALAMWFP RRYLPKIFRN 
       130        140        150        160        170        180 
DRGRFKAVVC VLSAITTCLA FIKPAINNIS LMILGLPCTA LLVAELKRCD NVRVFKLGLF 
       190        200        210        220        230        240 
SGLWWTLALF CWISDQAFCE LLSSFHFPYL HCVWHILICL ASYLGCVCFA YFDAASEIPE 
       250        260        270    
QGPVIRFWPS EKWAFIGVPY VSLLCAHKKS PVKIT

Isoforms

- Isoform 2 of Alkaline ceramidase 2

Sequence View

        10         20         30         40         50         60 
MGAPHWWDHL RAGSSEVDWC EDNYTIVPAI AEFYNTISNV LFFILPPICM CLFRQYATCF 
        70         80         90        100        110        120 
NSGIYLIWTL LVVVGIGSVY FHATLSFLGQ MLDELAILWV LMCALAMWFP RRYLPKIFRN 
       130        140        150        160        170        180 
DRGRFKAVVC VLSAITTCLA FIKPAINNIS LMILGLPCTA LLVAELKRCD NVRVFKLGLF 
       190        200        210        220        230        240 
SGLWWTLALF CWISDQAFCE LLSSFHFPYL HCVWHILICL ASYLGCVCFA YFDAASEIPE 
       250        260        270    
QGPVIRFWPS EKWAFIGVPY VSLLCAHKKS PVKIT



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8VD53-1-unknown MGAPHW... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8VD53-1-unknown MGAPHW... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt66135

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PVKIT 275 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...PVKIT 275 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt61753

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)