TopFIND 4.0

Q969Z0: FAST kinase domain-containing protein 4 {ECO:0000303|PubMed:20869947}

General Information

Protein names
- FAST kinase domain-containing protein 4 {ECO:0000303|PubMed:20869947}
- Cell cycle progression restoration protein 2
- Cell cycle progression protein 2
- Protein TBRG4
- Transforming growth factor beta regulator 4 {ECO:0000312|HGNC:HGNC:17443}
Gene names TBRG4
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q969Z0

7

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAAHLVKRCT CLLREAARQA PAMAPVGRLR LAWVAHKTLT SSATSPISHL PGSLMEPVEK 
        70         80         90        100        110        120 
ERASTPYIEK QVDHLIKKAT RPEELLELLG GSHDLDSNQA AMVLIRLSHL LSEKPEDKGL 
       130        140        150        160        170        180 
LIQDAHFHQL LCLLNSQIAS VWHGTLSKLL GSLYALGIPK ASKELQSVEQ EVRWRMRKLK 
       190        200        210        220        230        240 
YKHLAFLAES CATLSQEQHS QELLAELLTH LERRWTEIED SHTLVTVMMK VGHLSEPLMN 
       250        260        270        280        290        300 
RLEDKCLELV EHFGPNELRK VLVMLAAQSR RSVPLLRAIS YHLVQKPFSL TKDVLLDVAY 
       310        320        330        340        350        360 
AYGKLSFHQT QVSQRLATDL LSLMPSLTSG EVAHCAKSFA LLKWLSLPLF EAFAQHVLNR 
       370        380        390        400        410        420 
AQDITLPHLC SVLLAFARLN FHPDQEDQFF SLVHEKLGSE LPGLEPALQV DLVWALCVLQ 
       430        440        450        460        470        480 
QAREAELQAV LHPEFHIQFL GGKSQKDQNT FQKLLHINAT ALLEYPEYSG PLLPASAVAP 
       490        500        510        520        530        540 
GPSALDRKVT PLQKELQETL KGLLGSADKG SLEVATQYGW VLDAEVLLDS DGEFLPVRDF 
       550        560        570        580        590        600 
VAPHLAQPTG SQSPPPGSKR LAFLRWEFPN FNSRSKDLLG RFVLARRHIV AAGFLIVDVP 
       610        620        630    
FYEWLELKSE WQKGAYLKDK MRKAVAEELA K

Isoforms

- Isoform 2 of Protein TBRG4 - Isoform 2 of FAST kinase domain-containing protein 4

Sequence View

        10         20         30         40         50         60 
MAAHLVKRCT CLLREAARQA PAMAPVGRLR LAWVAHKTLT SSATSPISHL PGSLMEPVEK 
        70         80         90        100        110        120 
ERASTPYIEK QVDHLIKKAT RPEELLELLG GSHDLDSNQA AMVLIRLSHL LSEKPEDKGL 
       130        140        150        160        170        180 
LIQDAHFHQL LCLLNSQIAS VWHGTLSKLL GSLYALGIPK ASKELQSVEQ EVRWRMRKLK 
       190        200        210        220        230        240 
YKHLAFLAES CATLSQEQHS QELLAELLTH LERRWTEIED SHTLVTVMMK VGHLSEPLMN 
       250        260        270        280        290        300 
RLEDKCLELV EHFGPNELRK VLVMLAAQSR RSVPLLRAIS YHLVQKPFSL TKDVLLDVAY 
       310        320        330        340        350        360 
AYGKLSFHQT QVSQRLATDL LSLMPSLTSG EVAHCAKSFA LLKWLSLPLF EAFAQHVLNR 
       370        380        390        400        410        420 
AQDITLPHLC SVLLAFARLN FHPDQEDQFF SLVHEKLGSE LPGLEPALQV DLVWALCVLQ 
       430        440        450        460        470        480 
QAREAELQAV LHPEFHIQFL GGKSQKDQNT FQKLLHINAT ALLEYPEYSG PLLPASAVAP 
       490        500        510        520        530        540 
GPSALDRKVT PLQKELQETL KGLLGSADKG SLEVATQYGW VLDAEVLLDS DGEFLPVRDF 
       550        560        570        580        590        600 
VAPHLAQPTG SQSPPPGSKR LAFLRWEFPN FNSRSKDLLG RFVLARRHIV AAGFLIVDVP 
       610        620        630    
FYEWLELKSE WQKGAYLKDK MRKAVAEELA K         10         20         30         40         50         60 
MAAHLVKRCT CLLREAARQA PAMAPVGRLR LAWVAHKTLT SSATSPISHL PGSLMEPVEK 
        70         80         90        100        110        120 
ERASTPYIEK QVDHLIKKAT RPEELLELLG GSHDLDSNQA AMVLIRLSHL LSEKPEDKGL 
       130        140        150        160        170        180 
LIQDAHFHQL LCLLNSQIAS VWHGTLSKLL GSLYALGIPK ASKELQSVEQ EVRWRMRKLK 
       190        200        210        220        230        240 
YKHLAFLAES CATLSQEQHS QELLAELLTH LERRWTEIED SHTLVTVMMK VGHLSEPLMN 
       250        260        270        280        290        300 
RLEDKCLELV EHFGPNELRK VLVMLAAQSR RSVPLLRAIS YHLVQKPFSL TKDVLLDVAY 
       310        320        330        340        350        360 
AYGKLSFHQT QVSQRLATDL LSLMPSLTSG EVAHCAKSFA LLKWLSLPLF EAFAQHVLNR 
       370        380        390        400        410        420 
AQDITLPHLC SVLLAFARLN FHPDQEDQFF SLVHEKLGSE LPGLEPALQV DLVWALCVLQ 
       430        440        450        460        470        480 
QAREAELQAV LHPEFHIQFL GGKSQKDQNT FQKLLHINAT ALLEYPEYSG PLLPASAVAP 
       490        500        510        520        530        540 
GPSALDRKVT PLQKELQETL KGLLGSADKG SLEVATQYGW VLDAEVLLDS DGEFLPVRDF 
       550        560        570        580        590        600 
VAPHLAQPTG SQSPPPGSKR LAFLRWEFPN FNSRSKDLLG RFVLARRHIV AAGFLIVDVP 
       610        620        630    
FYEWLELKSE WQKGAYLKDK MRKAVAEELA K



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

7 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)