Q9BTZ2: Dehydrogenase/reductase SDR family member 4

General Information

Protein names	- Dehydrogenase/reductase SDR family member 4 - 1.1.1.184 - NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase - CR - PHCR - NADPH-dependent retinol dehydrogenase/reductase - NRDR - humNRDR - Peroxisomal short-chain alcohol dehydrogenase - PSCD - SCAD-SRL - Short chain dehydrogenase/reductase family 25C member 2 - Short-chain dehydrogenase/reductase family member 4
Gene names	DHRS4
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9BTZ2

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Dehydrogenase/reductase SDR family member 4 - Isoform 3 of Dehydrogenase/reductase SDR family member 4 - Isoform 4 of Dehydrogenase/reductase SDR family member 4 - Isoform 5 of Dehydrogenase/reductase SDR family member 4 - Isoform 6 of Dehydrogenase/reductase SDR family member 4 - Isoform 7 of Dehydrogenase/reductase SDR family member 4 - Isoform 8 of Dehydrogenase/reductase SDR family member 4

Sequence View

        10         20         30         40         50         60
MHKAGLLGLC ARAWNSVRMA SSGMTRRDPL ANKVALVTAS TDGIGFAIAR RLAQDGAHVV
        70         80         90        100        110        120
VSSRKQQNVD QAVATLQGEG LSVTGTVCHV GKAEDRERLV ATAVKLHGGI DILVSNAAVN
       130        140        150        160        170        180
PFFGSIMDVT EEVWDKTLDI NVKAPALMTK AVVPEMEKRG GGSVVIVSSI AAFSPSPGFS
       190        200        210        220        230        240
PYNVSKTALL GLTKTLAIEL APRNIRVNCL APGLIKTSFS RMLWMDKEKE ESMKETLRIR
       250        260        270
RLGEPEDCAG IVSFLCSEDA SYITGETVVV GGGTPSRL         10         20         30         40         50         60
MHKAGLLGLC ARAWNSVRMA SSGMTRRDPL ANKVALVTAS TDGIGFAIAR RLAQDGAHVV
        70         80         90        100        110        120
VSSRKQQNVD QAVATLQGEG LSVTGTVCHV GKAEDRERLV ATAVKLHGGI DILVSNAAVN
       130        140        150        160        170        180
PFFGSIMDVT EEVWDKTLDI NVKAPALMTK AVVPEMEKRG GGSVVIVSSI AAFSPSPGFS
       190        200        210        220        230        240
PYNVSKTALL GLTKTLAIEL APRNIRVNCL APGLIKTSFS RMLWMDKEKE ESMKETLRIR
       250        260        270
RLGEPEDCAG IVSFLCSEDA SYITGETVVV GGGTPSRL         10         20         30         40         50         60
MHKAGLLGLC ARAWNSVRMA SSGMTRRDPL ANKVALVTAS TDGIGFAIAR RLAQDGAHVV
        70         80         90        100        110        120
VSSRKQQNVD QAVATLQGEG LSVTGTVCHV GKAEDRERLV ATAVKLHGGI DILVSNAAVN
       130        140        150        160        170        180
PFFGSIMDVT EEVWDKTLDI NVKAPALMTK AVVPEMEKRG GGSVVIVSSI AAFSPSPGFS
       190        200        210        220        230        240
PYNVSKTALL GLTKTLAIEL APRNIRVNCL APGLIKTSFS RMLWMDKEKE ESMKETLRIR
       250        260        270
RLGEPEDCAG IVSFLCSEDA SYITGETVVV GGGTPSRL         10         20         30         40         50         60
MHKAGLLGLC ARAWNSVRMA SSGMTRRDPL ANKVALVTAS TDGIGFAIAR RLAQDGAHVV
        70         80         90        100        110        120
VSSRKQQNVD QAVATLQGEG LSVTGTVCHV GKAEDRERLV ATAVKLHGGI DILVSNAAVN
       130        140        150        160        170        180
PFFGSIMDVT EEVWDKTLDI NVKAPALMTK AVVPEMEKRG GGSVVIVSSI AAFSPSPGFS
       190        200        210        220        230        240
PYNVSKTALL GLTKTLAIEL APRNIRVNCL APGLIKTSFS RMLWMDKEKE ESMKETLRIR
       250        260        270
RLGEPEDCAG IVSFLCSEDA SYITGETVVV GGGTPSRL         10         20         30         40         50         60
MHKAGLLGLC ARAWNSVRMA SSGMTRRDPL ANKVALVTAS TDGIGFAIAR RLAQDGAHVV
        70         80         90        100        110        120
VSSRKQQNVD QAVATLQGEG LSVTGTVCHV GKAEDRERLV ATAVKLHGGI DILVSNAAVN
       130        140        150        160        170        180
PFFGSIMDVT EEVWDKTLDI NVKAPALMTK AVVPEMEKRG GGSVVIVSSI AAFSPSPGFS
       190        200        210        220        230        240
PYNVSKTALL GLTKTLAIEL APRNIRVNCL APGLIKTSFS RMLWMDKEKE ESMKETLRIR
       250        260        270
RLGEPEDCAG IVSFLCSEDA SYITGETVVV GGGTPSRL         10         20         30         40         50         60
MHKAGLLGLC ARAWNSVRMA SSGMTRRDPL ANKVALVTAS TDGIGFAIAR RLAQDGAHVV
        70         80         90        100        110        120
VSSRKQQNVD QAVATLQGEG LSVTGTVCHV GKAEDRERLV ATAVKLHGGI DILVSNAAVN
       130        140        150        160        170        180
PFFGSIMDVT EEVWDKTLDI NVKAPALMTK AVVPEMEKRG GGSVVIVSSI AAFSPSPGFS
       190        200        210        220        230        240
PYNVSKTALL GLTKTLAIEL APRNIRVNCL APGLIKTSFS RMLWMDKEKE ESMKETLRIR
       250        260        270
RLGEPEDCAG IVSFLCSEDA SYITGETVVV GGGTPSRL         10         20         30         40         50         60
MHKAGLLGLC ARAWNSVRMA SSGMTRRDPL ANKVALVTAS TDGIGFAIAR RLAQDGAHVV
        70         80         90        100        110        120
VSSRKQQNVD QAVATLQGEG LSVTGTVCHV GKAEDRERLV ATAVKLHGGI DILVSNAAVN
       130        140        150        160        170        180
PFFGSIMDVT EEVWDKTLDI NVKAPALMTK AVVPEMEKRG GGSVVIVSSI AAFSPSPGFS
       190        200        210        220        230        240
PYNVSKTALL GLTKTLAIEL APRNIRVNCL APGLIKTSFS RMLWMDKEKE ESMKETLRIR
       250        260        270
RLGEPEDCAG IVSFLCSEDA SYITGETVVV GGGTPSRL

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9BTZ2-1-unknown	MHKAGL...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9BTZ2-1-unknown	MHKAGL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt72726
Q9BTZ2-1-unknown	MHKAGL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt72727
Q9BTZ2-1-unknown	MHKAGL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt72728
Q9BTZ2-1-unknown	MHKAGL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt72729
Q9BTZ2-1-unknown	MHKAGL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt72731
Q9BTZ2-19-unknown	MASSGM...	19	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt72732
Q9BTZ2-19-unknown	MASSGM...	19	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt97493
Q9BTZ2-19-unknown	MASSGM...	19	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt97494
Q9BTZ2-19-unknown	MASSGM...	19	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt97495
Q9BTZ2-19-unknown	MASSGM...	19	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt97496
Q9BTZ2-19-unknown	MASSGM...	19	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt97497

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TPSRL	278	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...TPSRL	278	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt68348
...TPSRL	278	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt68345
...TPSRL	278	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt68344
...TPSRL	278	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt68347
...TPSRL	278	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt68350
...TPSRL	278	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt68346

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)