Q9H992: E3 ubiquitin-protein ligase MARCH7

General Information

Protein names	- E3 ubiquitin-protein ligase MARCH7 - 2.3.2.27 - Axotrophin - Membrane-associated RING finger protein 7 - Membrane-associated RING-CH protein VII - MARCH-VII - RING finger protein 177 - RING-type E3 ubiquitin transferase MARCH7 {ECO:0000305}
Gene names	MARCH7
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9H992

2 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MESKPSRIPR RISVQPSSSL SARMMSGSRG SSLNDTYHSR DSSFRLDSEY QSTSASASAS
        70         80         90        100        110        120
PFQSAWYSES EITQGARSRS QNQQRDHDSK RPKLSCTNCT TSAGRNVGNG LNTLSDSSWR
       130        140        150        160        170        180
HSQVPRSSSM VLGSFGTDLM RERRDLERRT DSSISNLMDY SHRSGDFTTS SYVQDRVPSY
       190        200        210        220        230        240
SQGARPKENS MSTLQLNTSS TNHQLPSEHQ TILSSRDSRN SLRSNFSSRE SESSRSNTQP
       250        260        270        280        290        300
GFSYSSSRDE APIISNSERV VSSQRPFQES SDNEGRRTTR RLLSRIASSM SSTFFSRRSS
       310        320        330        340        350        360
QDSLNTRSLN SENSYVSPRI LTASQSRSNV PSASEVPDNR ASEASQGFRF LRRRWGLSSL
       370        380        390        400        410        420
SHNHSSESDS ENFNQESEGR NTGPWLSSSL RNRCTPLFSR RRREGRDESS RIPTSDTSSR
       430        440        450        460        470        480
SHIFRRESNE VVHLEAQNDP LGAAANRPQA SAASSSATTG GSTSDSAQGG RNTGISGILP
       490        500        510        520        530        540
GSLFRFAVPP ALGSNLTDNV MITVDIIPSG WNSADGKSDK TKSAPSRDPE RLQKIKESLL
       550        560        570        580        590        600
LEDSEEEEGD LCRICQMAAA SSSNLLIEPC KCTGSLQYVH QDCMKKWLQA KINSGSSLEA
       610        620        630        640        650        660
VTTCELCKEK LELNLEDFDI HELHRAHANE QAEYEFISSG LYLVVLLHLC EQSFSDMMGN
       670        680        690        700
TNEPSTRVRF INLARTLQAH MEDLETSEDD SEEDGDHNRT FDIA

Isoforms

- Isoform 2 of E3 ubiquitin-protein ligase MARCH7

Sequence View

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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9H992-1-Acetylation	MESKPS...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9H992-1-Acetylation	MESKPS...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q9H992-1-Acetylation	MESKPS...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9H992-568-unknown	EPCKCT...	568		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000391493
Q9H992-568-unknown	EPCKCT...	568		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt132107

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TNCTTS	101	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000392862
...TNCTTS	101	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113094
...TFDIA	704	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...TFDIA	704	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt76037

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)