TopFIND 4.0

Q9Y4E6: WD repeat-containing protein 7

General Information

Protein names
- WD repeat-containing protein 7
- Rabconnectin-3 beta
- TGF-beta resistance-associated protein TRAG
Gene names WDR7
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9Y4E6

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAGNSLVLPI VLWGRKAPTH CISAVLLTDD GATIVTGCHD GQICLWDLSV ELQINPRALL 
        70         80         90        100        110        120 
FGHTASITCL SKACASSDKQ YIVSASESGE MCLWDVSDGR CIEFTKLACT HTGIQFYQFS 
       130        140        150        160        170        180 
VGNQREGRLL CHGHYPEILV VDATSLEVLY SLVSKISPDW ISSMSIIRSH RTQEDTVVAL 
       190        200        210        220        230        240 
SVTGILKVWI VTSEISDMQD TEPIFEEESK PIYCQNCQSI SFCAFTQRSL LVVCSKYWRV 
       250        260        270        280        290        300 
FDAGDYSLLC SGPSENGQTW TGGDFVSSDK VIIWTENGQS YIYKLPASCL PASDSFRSDV 
       310        320        330        340        350        360 
GKAVENLIPP VQHILLDRKD KELLICPPVT RFFYGCREYF HKLLIQGDSS GRLNIWNISD 
       370        380        390        400        410        420 
TADKQGSEEG LAMTTSISLQ EAFDKLNPCP AGIIDQLSVI PNSNEPLKVT ASVYIPAHGR 
       430        440        450        460        470        480 
LVCGREDGSI VIVPATQTAI VQLLQGEHML RRGWPPHRTL RGHRNKVTCL LYPHQVSARY 
       490        500        510        520        530        540 
DQRYLISGGV DFSVIIWDIF SGEMKHIFCV HGGEITQLLV PPENCSARVQ HCICSVASDH 
       550        560        570        580        590        600 
SVGLLSLREK KCIMLASRHL FPIQVIKWRP SDDYLVVGCS DGSVYVWQMD TGALDRCVMG 
       610        620        630        640        650        660 
ITAVEILNAC DEAVPAAVDS LSHPAVNLKQ AMTRRSLAAL KNMAHHKLQT LATNLLASEA 
       670        680        690        700        710        720 
SDKGNLPKYS HNSLMVQAIK TNLTDPDIHV LFFDVEALII QLLTEEASRP NTALISPENL 
       730        740        750        760        770        780 
QKASGSSDKG GSFLTGKRAA VLFQQVKETI KENIKEHLLD DEEEDEEIMR QRREESDPEY 
       790        800        810        820        830        840 
RSSKSKPLTL LEYNLTMDTA KLFMSCLHAW GLNEVLDEVC LDRLGMLKPH CTVSFGLLSR 
       850        860        870        880        890        900 
GGHMSLMLPG YNQPACKLSH GKTEVGRKLP ASEGVGKGTY GVSRAVTTQH LLSIISLANT 
       910        920        930        940        950        960 
LMSMTNATFI GDHMKKGPTR PPRPSTPDLS KARGSPPTSS NIVQGQIKQV AAPVVSARSD 
       970        980        990       1000       1010       1020 
ADHSGSDPPS APALHTCFLV NEGWSQLAAM HCVMLPDLLG LDKFRPPLLE MLARRWQDRC 
      1030       1040       1050       1060       1070       1080 
LEVREAAQAL LLAELRRIEQ AGRKEAIDAW APYLPQYIDH VISPGVTSEA AQTITTAPDA 
      1090       1100       1110       1120       1130       1140 
SGPEAKVQEE EHDLVDDDIT TGCLSSVPQM KKISTSYEER RKQATAIVLL GVIGAEFGAE 
      1150       1160       1170       1180       1190       1200 
IEPPKLLTRP RSSSQIPEGF GLTSGGSNYS LARHTCKALT FLLLQPPSPK LPPHSTIRRT 
      1210       1220       1230       1240       1250       1260 
AIDLIGRGFT VWEPYMDVSA VLMGLLELCA DAEKQLANIT MGLPLSPAAD SARSARHALS 
      1270       1280       1290       1300       1310       1320 
LIATARPPAF ITTIAKEVHR HTALAANTQS QQNMHTTTLA RAKGEILRVI EILIEKMPTD 
      1330       1340       1350       1360       1370       1380 
VVDLLVEVMD IIMYCLEGSL VKKKGLQECF PAICRFYMVS YYERNHRIAV GARHGSVALY 
      1390       1400       1410       1420       1430       1440 
DIRTGKCQTI HGHKGPITAV AFAPDGRYLA TYSNTDSHIS FWQMNTSLLG SIGMLNSAPQ 
      1450       1460       1470       1480       1490    
LRCIKTYQVP PVQPASPGSH NALKLARLIW TSNRNVILMA HDGKEHRFMV 

Isoforms

- Isoform 2 of WD repeat-containing protein 7

Sequence View

        10         20         30         40         50         60 
MAGNSLVLPI VLWGRKAPTH CISAVLLTDD GATIVTGCHD GQICLWDLSV ELQINPRALL 
        70         80         90        100        110        120 
FGHTASITCL SKACASSDKQ YIVSASESGE MCLWDVSDGR CIEFTKLACT HTGIQFYQFS 
       130        140        150        160        170        180 
VGNQREGRLL CHGHYPEILV VDATSLEVLY SLVSKISPDW ISSMSIIRSH RTQEDTVVAL 
       190        200        210        220        230        240 
SVTGILKVWI VTSEISDMQD TEPIFEEESK PIYCQNCQSI SFCAFTQRSL LVVCSKYWRV 
       250        260        270        280        290        300 
FDAGDYSLLC SGPSENGQTW TGGDFVSSDK VIIWTENGQS YIYKLPASCL PASDSFRSDV 
       310        320        330        340        350        360 
GKAVENLIPP VQHILLDRKD KELLICPPVT RFFYGCREYF HKLLIQGDSS GRLNIWNISD 
       370        380        390        400        410        420 
TADKQGSEEG LAMTTSISLQ EAFDKLNPCP AGIIDQLSVI PNSNEPLKVT ASVYIPAHGR 
       430        440        450        460        470        480 
LVCGREDGSI VIVPATQTAI VQLLQGEHML RRGWPPHRTL RGHRNKVTCL LYPHQVSARY 
       490        500        510        520        530        540 
DQRYLISGGV DFSVIIWDIF SGEMKHIFCV HGGEITQLLV PPENCSARVQ HCICSVASDH 
       550        560        570        580        590        600 
SVGLLSLREK KCIMLASRHL FPIQVIKWRP SDDYLVVGCS DGSVYVWQMD TGALDRCVMG 
       610        620        630        640        650        660 
ITAVEILNAC DEAVPAAVDS LSHPAVNLKQ AMTRRSLAAL KNMAHHKLQT LATNLLASEA 
       670        680        690        700        710        720 
SDKGNLPKYS HNSLMVQAIK TNLTDPDIHV LFFDVEALII QLLTEEASRP NTALISPENL 
       730        740        750        760        770        780 
QKASGSSDKG GSFLTGKRAA VLFQQVKETI KENIKEHLLD DEEEDEEIMR QRREESDPEY 
       790        800        810        820        830        840 
RSSKSKPLTL LEYNLTMDTA KLFMSCLHAW GLNEVLDEVC LDRLGMLKPH CTVSFGLLSR 
       850        860        870        880        890        900 
GGHMSLMLPG YNQPACKLSH GKTEVGRKLP ASEGVGKGTY GVSRAVTTQH LLSIISLANT 
       910        920        930        940        950        960 
LMSMTNATFI GDHMKKGPTR PPRPSTPDLS KARGSPPTSS NIVQGQIKQV AAPVVSARSD 
       970        980        990       1000       1010       1020 
ADHSGSDPPS APALHTCFLV NEGWSQLAAM HCVMLPDLLG LDKFRPPLLE MLARRWQDRC 
      1030       1040       1050       1060       1070       1080 
LEVREAAQAL LLAELRRIEQ AGRKEAIDAW APYLPQYIDH VISPGVTSEA AQTITTAPDA 
      1090       1100       1110       1120       1130       1140 
SGPEAKVQEE EHDLVDDDIT TGCLSSVPQM KKISTSYEER RKQATAIVLL GVIGAEFGAE 
      1150       1160       1170       1180       1190       1200 
IEPPKLLTRP RSSSQIPEGF GLTSGGSNYS LARHTCKALT FLLLQPPSPK LPPHSTIRRT 
      1210       1220       1230       1240       1250       1260 
AIDLIGRGFT VWEPYMDVSA VLMGLLELCA DAEKQLANIT MGLPLSPAAD SARSARHALS 
      1270       1280       1290       1300       1310       1320 
LIATARPPAF ITTIAKEVHR HTALAANTQS QQNMHTTTLA RAKGEILRVI EILIEKMPTD 
      1330       1340       1350       1360       1370       1380 
VVDLLVEVMD IIMYCLEGSL VKKKGLQECF PAICRFYMVS YYERNHRIAV GARHGSVALY 
      1390       1400       1410       1420       1430       1440 
DIRTGKCQTI HGHKGPITAV AFAPDGRYLA TYSNTDSHIS FWQMNTSLLG SIGMLNSAPQ 
      1450       1460       1470       1480       1490    
LRCIKTYQVP PVQPASPGSH NALKLARLIW TSNRNVILMA HDGKEHRFMV 



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9Y4E6-1-unknown MAGNSL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9Y4E6-1-unknown MAGNSL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt94487

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...HRFMV 1490 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...HRFMV 1490 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt90105

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)