Q9Y6N9: Harmonin

General Information

Protein names	- Harmonin - Antigen NY-CO-38/NY-CO-37 - Autoimmune enteropathy-related antigen AIE-75 - Protein PDZ-73 - Renal carcinoma antigen NY-REN-3 - Usher syndrome type-1C protein
Gene names	USH1C
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Y6N9

2 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Harmonin - Isoform 3 of Harmonin - Isoform 4 of Harmonin - Isoform 5 of Harmonin

Sequence View

        10         20         30         40         50         60
MDRKVAREFR HKVDFLIEND AEKDYLYDVL RMYHQTMDVA VLVGDLKLVI NEPSRLPLFD
        70         80         90        100        110        120
AIRPLIPLKH QVEYDQLTPR RSRKLKEVRL DRLHPEGLGL SVRGGLEFGC GLFISHLIKG
       130        140        150        160        170        180
GQADSVGLQV GDEIVRINGY SISSCTHEEV INLIRTKKTV SIKVRHIGLI PVKSSPDEPL
       190        200        210        220        230        240
TWQYVDQFVS ESGGVRGSLG SPGNRENKEK KVFISLVGSR GLGCSISSGP IQKPGIFISH
       250        260        270        280        290        300
VKPGSLSAEV GLEIGDQIVE VNGVDFSNLD HKEAVNVLKS SRSLTISIVA AAGRELFMTD
       310        320        330        340        350        360
RERLAEARQR ELQRQELLMQ KRLAMESNKI LQEQQEMERQ RRKEIAQKAA EENERYRKEM
       370        380        390        400        410        420
EQIVEEEEKF KKQWEEDWGS KEQLLLPKTI TAEVHPVPLR KPKYDQGVEP ELEPADDLDG
       430        440        450        460        470        480
GTEEQGEQDF RKYEEGFDPY SMFTPEQIMG KDVRLLRIKK EGSLDLALEG GVDSPIGKVV
       490        500        510        520        530        540
VSAVYERGAA ERHGGIVKGD EIMAINGKIV TDYTLAEAEA ALQKAWNQGG DWIDLVVAVC
       550
PPKEYDDELT FF         10         20         30         40         50         60
MDRKVAREFR HKVDFLIEND AEKDYLYDVL RMYHQTMDVA VLVGDLKLVI NEPSRLPLFD
        70         80         90        100        110        120
AIRPLIPLKH QVEYDQLTPR RSRKLKEVRL DRLHPEGLGL SVRGGLEFGC GLFISHLIKG
       130        140        150        160        170        180
GQADSVGLQV GDEIVRINGY SISSCTHEEV INLIRTKKTV SIKVRHIGLI PVKSSPDEPL
       190        200        210        220        230        240
TWQYVDQFVS ESGGVRGSLG SPGNRENKEK KVFISLVGSR GLGCSISSGP IQKPGIFISH
       250        260        270        280        290        300
VKPGSLSAEV GLEIGDQIVE VNGVDFSNLD HKEAVNVLKS SRSLTISIVA AAGRELFMTD
       310        320        330        340        350        360
RERLAEARQR ELQRQELLMQ KRLAMESNKI LQEQQEMERQ RRKEIAQKAA EENERYRKEM
       370        380        390        400        410        420
EQIVEEEEKF KKQWEEDWGS KEQLLLPKTI TAEVHPVPLR KPKYDQGVEP ELEPADDLDG
       430        440        450        460        470        480
GTEEQGEQDF RKYEEGFDPY SMFTPEQIMG KDVRLLRIKK EGSLDLALEG GVDSPIGKVV
       490        500        510        520        530        540
VSAVYERGAA ERHGGIVKGD EIMAINGKIV TDYTLAEAEA ALQKAWNQGG DWIDLVVAVC
       550
PPKEYDDELT FF         10         20         30         40         50         60
MDRKVAREFR HKVDFLIEND AEKDYLYDVL RMYHQTMDVA VLVGDLKLVI NEPSRLPLFD
        70         80         90        100        110        120
AIRPLIPLKH QVEYDQLTPR RSRKLKEVRL DRLHPEGLGL SVRGGLEFGC GLFISHLIKG
       130        140        150        160        170        180
GQADSVGLQV GDEIVRINGY SISSCTHEEV INLIRTKKTV SIKVRHIGLI PVKSSPDEPL
       190        200        210        220        230        240
TWQYVDQFVS ESGGVRGSLG SPGNRENKEK KVFISLVGSR GLGCSISSGP IQKPGIFISH
       250        260        270        280        290        300
VKPGSLSAEV GLEIGDQIVE VNGVDFSNLD HKEAVNVLKS SRSLTISIVA AAGRELFMTD
       310        320        330        340        350        360
RERLAEARQR ELQRQELLMQ KRLAMESNKI LQEQQEMERQ RRKEIAQKAA EENERYRKEM
       370        380        390        400        410        420
EQIVEEEEKF KKQWEEDWGS KEQLLLPKTI TAEVHPVPLR KPKYDQGVEP ELEPADDLDG
       430        440        450        460        470        480
GTEEQGEQDF RKYEEGFDPY SMFTPEQIMG KDVRLLRIKK EGSLDLALEG GVDSPIGKVV
       490        500        510        520        530        540
VSAVYERGAA ERHGGIVKGD EIMAINGKIV TDYTLAEAEA ALQKAWNQGG DWIDLVVAVC
       550
PPKEYDDELT FF         10         20         30         40         50         60
MDRKVAREFR HKVDFLIEND AEKDYLYDVL RMYHQTMDVA VLVGDLKLVI NEPSRLPLFD
        70         80         90        100        110        120
AIRPLIPLKH QVEYDQLTPR RSRKLKEVRL DRLHPEGLGL SVRGGLEFGC GLFISHLIKG
       130        140        150        160        170        180
GQADSVGLQV GDEIVRINGY SISSCTHEEV INLIRTKKTV SIKVRHIGLI PVKSSPDEPL
       190        200        210        220        230        240
TWQYVDQFVS ESGGVRGSLG SPGNRENKEK KVFISLVGSR GLGCSISSGP IQKPGIFISH
       250        260        270        280        290        300
VKPGSLSAEV GLEIGDQIVE VNGVDFSNLD HKEAVNVLKS SRSLTISIVA AAGRELFMTD
       310        320        330        340        350        360
RERLAEARQR ELQRQELLMQ KRLAMESNKI LQEQQEMERQ RRKEIAQKAA EENERYRKEM
       370        380        390        400        410        420
EQIVEEEEKF KKQWEEDWGS KEQLLLPKTI TAEVHPVPLR KPKYDQGVEP ELEPADDLDG
       430        440        450        460        470        480
GTEEQGEQDF RKYEEGFDPY SMFTPEQIMG KDVRLLRIKK EGSLDLALEG GVDSPIGKVV
       490        500        510        520        530        540
VSAVYERGAA ERHGGIVKGD EIMAINGKIV TDYTLAEAEA ALQKAWNQGG DWIDLVVAVC
       550
PPKEYDDELT FF

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9Y6N9-1-unknown	MDRKVA...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9Y6N9-1-unknown	MDRKVA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt93986
Q9Y6N9-1-unknown	MDRKVA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt93987
Q9Y6N9-1-unknown	MDRKVA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt93988
Q9Y6N9-32-unknown	MYHQTM...	32	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt93985
Q9Y6N9-32-unknown	MYHQTM...	32	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt97792
Q9Y6N9-32-unknown	MYHQTM...	32	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt97793
Q9Y6N9-32-unknown	MYHQTM...	32	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt97794

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LRKPKY	403	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt89604
...LRKPKY	403	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92677
...LRKPKY	403	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92676
...LRKPKY	403	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92675
...ELTFF	552	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...ELTFF	552	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt89603
...ELTFF	552	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt89605

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)