TopFIND 4.0

Q9Z188: Dual specificity tyrosine-phosphorylation-regulated kinase 1B

General Information

Protein names
- Dual specificity tyrosine-phosphorylation-regulated kinase 1B
- 2.7.12.1
Gene names Dyrk1b
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q9Z188

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAVPPGHGPF SGFPGPQEHT QVLPDVRLLP RRLPLAFRDA ASAPLRKLSV DLIKTYKHIN 
        70         80         90        100        110        120 
EVYYAKKKRR AQQAPPQDSS TKKEKKVLNH GYDDDNHDYI VRSGERWLER YEIDSLIGKG 
       130        140        150        160        170        180 
SFGQVVKAYD HQTQELVAIK IIKNKKAFLN QAQIELRLLE LMNQHDTEMK YYIVHLKRHF 
       190        200        210        220        230        240 
MFRNHLCLVF ELLSYNLYDL LRNTHFRGVS LNLTRKLAQQ LCTALLFLAT PELSIIHCDL 
       250        260        270        280        290        300 
KPENILLCNP KRSAIKIVDF GSSCQLGQRI YQYIQSRFYR SPEVLLGTPY DLAIDMWSLG 
       310        320        330        340        350        360 
CILVEMHTGE PLFSGSNEVD QMSRIVEVLG IPPAPMLEQA PKARKYFERL PGGGWTLRRT 
       370        380        390        400        410        420 
KELRKDYQGP GTRRLQEVLG VQTGGPGGRR AGEPGHSPAD YLRFQDLVLR MLEYEPAARI 
       430        440        450        460        470        480 
SPLGALQHGF FRRTADEATN TGPAGSSAST SPAPLDTCPS SSTASSISSS GGSSGSSNDN 
       490        500        510        520        530        540 
RAYRYSNRYC GGPGPPITDC EMNSPQVLPS QPLRPWAGGD VPHKTHQAPI SASTLPGTGA 
       550        560        570        580        590        600 
QLPPLPRCLG RPPSPTSPPP PELMDVSLVG SPPDCSPPPP APAPQHPAAS ALRTRMTGGR 
       610        620    
PPLPPPDDPA TLGPRLGLHG VPQSTAASS

Isoforms

- Isoform 2 of Dual specificity tyrosine-phosphorylation-regulated kinase 1B - Isoform 3 of Dual specificity tyrosine-phosphorylation-regulated kinase 1B

Sequence View

        10         20         30         40         50         60 
MAVPPGHGPF SGFPGPQEHT QVLPDVRLLP RRLPLAFRDA ASAPLRKLSV DLIKTYKHIN 
        70         80         90        100        110        120 
EVYYAKKKRR AQQAPPQDSS TKKEKKVLNH GYDDDNHDYI VRSGERWLER YEIDSLIGKG 
       130        140        150        160        170        180 
SFGQVVKAYD HQTQELVAIK IIKNKKAFLN QAQIELRLLE LMNQHDTEMK YYIVHLKRHF 
       190        200        210        220        230        240 
MFRNHLCLVF ELLSYNLYDL LRNTHFRGVS LNLTRKLAQQ LCTALLFLAT PELSIIHCDL 
       250        260        270        280        290        300 
KPENILLCNP KRSAIKIVDF GSSCQLGQRI YQYIQSRFYR SPEVLLGTPY DLAIDMWSLG 
       310        320        330        340        350        360 
CILVEMHTGE PLFSGSNEVD QMSRIVEVLG IPPAPMLEQA PKARKYFERL PGGGWTLRRT 
       370        380        390        400        410        420 
KELRKDYQGP GTRRLQEVLG VQTGGPGGRR AGEPGHSPAD YLRFQDLVLR MLEYEPAARI 
       430        440        450        460        470        480 
SPLGALQHGF FRRTADEATN TGPAGSSAST SPAPLDTCPS SSTASSISSS GGSSGSSNDN 
       490        500        510        520        530        540 
RAYRYSNRYC GGPGPPITDC EMNSPQVLPS QPLRPWAGGD VPHKTHQAPI SASTLPGTGA 
       550        560        570        580        590        600 
QLPPLPRCLG RPPSPTSPPP PELMDVSLVG SPPDCSPPPP APAPQHPAAS ALRTRMTGGR 
       610        620    
PPLPPPDDPA TLGPRLGLHG VPQSTAASS         10         20         30         40         50         60 
MAVPPGHGPF SGFPGPQEHT QVLPDVRLLP RRLPLAFRDA ASAPLRKLSV DLIKTYKHIN 
        70         80         90        100        110        120 
EVYYAKKKRR AQQAPPQDSS TKKEKKVLNH GYDDDNHDYI VRSGERWLER YEIDSLIGKG 
       130        140        150        160        170        180 
SFGQVVKAYD HQTQELVAIK IIKNKKAFLN QAQIELRLLE LMNQHDTEMK YYIVHLKRHF 
       190        200        210        220        230        240 
MFRNHLCLVF ELLSYNLYDL LRNTHFRGVS LNLTRKLAQQ LCTALLFLAT PELSIIHCDL 
       250        260        270        280        290        300 
KPENILLCNP KRSAIKIVDF GSSCQLGQRI YQYIQSRFYR SPEVLLGTPY DLAIDMWSLG 
       310        320        330        340        350        360 
CILVEMHTGE PLFSGSNEVD QMSRIVEVLG IPPAPMLEQA PKARKYFERL PGGGWTLRRT 
       370        380        390        400        410        420 
KELRKDYQGP GTRRLQEVLG VQTGGPGGRR AGEPGHSPAD YLRFQDLVLR MLEYEPAARI 
       430        440        450        460        470        480 
SPLGALQHGF FRRTADEATN TGPAGSSAST SPAPLDTCPS SSTASSISSS GGSSGSSNDN 
       490        500        510        520        530        540 
RAYRYSNRYC GGPGPPITDC EMNSPQVLPS QPLRPWAGGD VPHKTHQAPI SASTLPGTGA 
       550        560        570        580        590        600 
QLPPLPRCLG RPPSPTSPPP PELMDVSLVG SPPDCSPPPP APAPQHPAAS ALRTRMTGGR 
       610        620    
PPLPPPDDPA TLGPRLGLHG VPQSTAASS



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9Z188-1-unknown MAVPPG... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9Z188-1-unknown MAVPPG... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt73445
    Q9Z188-1-unknown MAVPPG... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt106643

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)