Evidence Source
| Description | fibroblast secretome MMP2 -/- cells 4plex iTRAQ labeling of controls and protease treated proteomes. Termini with a reported ratio between -0.75 and 1.5 between all conditions are reported here (resembling native termini that are not affected by the studied protease) |
|---|---|
Method |
N-TAILS |
Experimental system |
cell culture |
Perturbation |
|
Protease inhibitor(s) used |
|
Directness |
direct |
Physiological relevance |
likely |
Evidence Code(s) |
|
Database / Laboratory |
- Lab: Overall CM. |
Raw data repository |
Evidence for:
492
N-termini
0
C-termini
Publication(s) |
A statistics-based platform for quantitative N-terminome analysis and identification of protease cleavage products. auf dem Keller U, Prudova A, Gioia M, Butler GS, Overall CM Mol Cell Proteomics. 2010 May;9(5):912-27. doi: 10.1074/mcp.M000032-MCP201. Epub 2010 Mar 20. PMID: 20305283 |
|---|