TopFIND 4.0

Evidence Source

Description Jurkat treated with staurosporine or trail, extracts combined, and free n-termini identified

Method


Experimental system

cell culture

Perturbation

apoptosis induced by staurosporin

Protease inhibitor(s) used


Directness

direct

Physiological relevance

yes

Evidence Code(s)


Database / Laboratory

    - Lab: Wells

Raw data repository

http://wellslab.ucsf.edu/degrabase/

Evidence for:

7853

N-termini

0

C-termini


Publication(s)

The DegraBase: a database of proteolysis in healthy and apoptotic human cells.

Crawford ED, Seaman JE, Agard N, Hsu GW, Julien O, Mahrus S, Nguyen H, Shimbo K, Yoshihara HA, Zhuang M, Chalkley RJ, Wells JA

Mol Cell Proteomics. 2013 Mar;12(3):813-24. doi: 10.1074/mcp.O112.024372. Epub 2012 Dec 20. PMID: 23264352