Evidence Source
| Description | MM1s, DB and Jurkat treated with staurosporine, doxorubicin and bortezomib, extracts combined, and free n-termini identified |
|---|---|
Method |
|
Experimental system |
cell culture |
Perturbation |
apoptosis induced by staurosporine, doxorubicin and bortezomib |
Protease inhibitor(s) used |
|
Directness |
direct |
Physiological relevance |
yes |
Evidence Code(s) |
|
Database / Laboratory |
- Lab: Wells |
Raw data repository |
http://wellslab.ucsf.edu/degrabase/ |
Evidence for:
1997
N-termini
0
C-termini
Publication(s) |
The DegraBase: a database of proteolysis in healthy and apoptotic human cells. Crawford ED, Seaman JE, Agard N, Hsu GW, Julien O, Mahrus S, Nguyen H, Shimbo K, Yoshihara HA, Zhuang M, Chalkley RJ, Wells JA Mol Cell Proteomics. 2013 Mar;12(3):813-24. doi: 10.1074/mcp.O112.024372. Epub 2012 Dec 20. PMID: 23264352 |
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