Evidence Source
Description | Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 25-54,89-110 |
---|---|
Method |
Protease identification: VT | Substrate identification: MS |
Experimental system |
unknown |
Perturbation |
none |
Protease inhibitor(s) used |
|
Directness |
unknown |
Physiological relevance |
yes |
Evidence Code(s) |
inferred from experiment |
Database / Laboratory |
- Lab: Authier F - DB: MEROPS |
Raw data repository |
Evidence for:
0
N-termini
0
C-termini
Publication(s) |
Endosomal proteolysis of internalised [ArgA0]-human insulin at neutral pH generates the mature insulin peptide in rat liver in vivo. Kouach M, Desbuquois B, Authier F Diabetologia. 2009 Dec;52(12):2621-32. doi: 10.1007/s00125-009-1551-0. Epub 2009 Oct 16. PMID: 19834685 |
---|