Evidence Source
| Description | Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 32-2386 |
|---|---|
Method |
Protease identification: VT | Substrate identification: NT |
Experimental system |
unknown |
Perturbation |
none |
Protease inhibitor(s) used |
|
Directness |
unknown |
Physiological relevance |
yes |
Evidence Code(s) |
inferred from experiment |
Database / Laboratory |
- Lab: Tortorella MD - DB: MEROPS |
Raw data repository |
Evidence for:
0
N-termini
0
C-termini
Publication(s) |
ADAM-8 isolated from human osteoarthritic chondrocytes cleaves fibronectin at Ala(271). Zack MD, Malfait AM, Skepner AP, Yates MP, Griggs DW, Hall T, Hills RL, Alston JT, Nemirovskiy OV, Radabaugh MR, Leone JW, Arner EC, Tortorella MD Arthritis Rheum. 2009 Sep;60(9):2704-13. doi: 10.1002/art.24753. PMID: 19714641 |
|---|