Evidence Source

Description	Imported from Merops: Merops-evidence: experimental \| Merops-type: physiological \| Merops-range: 17-2415
Method
Experimental system	unknown
Perturbation	none
Protease inhibitor(s) used
Directness	unknown
Physiological relevance	yes
Evidence Code(s)	inferred from experiment
Database / Laboratory	- Lab: Murphy G - DB: MEROPS
Raw data repository

Evidence for:

Publication(s)	TIMP-3 inhibition of ADAMTS-4 (Aggrecanase-1) is modulated by interactions between aggrecan and the C-terminal domain of ADAMTS-4. Wayne GJ, Deng SJ, Amour A, Borman S, Matico R, Carter HL, Murphy G J Biol Chem. 2007 Jul 20;282(29):20991-8. Epub 2007 Apr 30. PMID: 17470431

Publication(s)

TIMP-3 inhibition of ADAMTS-4 (Aggrecanase-1) is modulated by interactions between aggrecan and the C-terminal domain of ADAMTS-4.

Wayne GJ, Deng SJ, Amour A, Borman S, Matico R, Carter HL, Murphy G