TopFIND 4.0

Evidence Source

Description Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 18-770

Method


Experimental system

unknown

Perturbation

none

Protease inhibitor(s) used


Directness

unknown

Physiological relevance

yes

Evidence Code(s)

    inferred from experiment

Database / Laboratory

Raw data repository

Evidence for:

0

N-termini

0

C-termini


Publication(s)

Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor protein.

Lin X, Koelsch G, Wu S, Downs D, Dashti A, Tang J

Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1456-60. PMID: 10677483