Evidence Source
Description | Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 1-3142 |
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Method |
|
Experimental system |
unknown |
Perturbation |
none |
Protease inhibitor(s) used |
|
Directness |
unknown |
Physiological relevance |
yes |
Evidence Code(s) |
inferred from experiment |
Database / Laboratory |
- Lab: Ellerby LM - DB: MEROPS |
Raw data repository |
Evidence for:
0
N-termini
0
C-termini
Publication(s) |
Inhibition of calpain cleavage of huntingtin reduces toxicity: accumulation of calpain/caspase fragments in the nucleus. Gafni J, Hermel E, Young JE, Wellington CL, Hayden MR, Ellerby LM J Biol Chem. 2004 May 7;279(19):20211-20. Epub 2004 Feb 23. PMID: 14981075 |
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