Evidence Source

Description	Imported from Merops: Merops-evidence: experimental \| Merops-type: physiological \| Merops-range: 1-193
Method
Experimental system	unknown
Perturbation	none
Protease inhibitor(s) used
Directness	unknown
Physiological relevance	yes
Evidence Code(s)	inferred from experiment
Database / Laboratory	- Lab: Fox JE - DB: MEROPS
Raw data repository

Evidence for:

Publication(s)	Calpain cleaves RhoA generating a dominant-negative form that inhibits integrin-induced actin filament assembly and cell spreading. Kulkarni S, Goll DE, Fox JE J Biol Chem. 2002 Jul 5;277(27):24435-41. Epub 2002 Apr 18. PMID: 11964413

Publication(s)

Calpain cleaves RhoA generating a dominant-negative form that inhibits integrin-induced actin filament assembly and cell spreading.

Kulkarni S, Goll DE, Fox JE