TopFIND 4.0

Evidence Source

Description Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 1-2391

Method

Protease identification: IN | Substrate identification: NT

Experimental system

unknown

Perturbation

none

Protease inhibitor(s) used


Directness

unknown

Physiological relevance

yes

Evidence Code(s)

    inferred from experiment

Database / Laboratory

Raw data repository

Evidence for:

0

N-termini

0

C-termini


Publication(s)

Deimination of human filaggrin-2 promotes its proteolysis by calpain 1.

Hsu CY, Henry J, Raymond AA, Mechin MC, Pendaries V, Nassar D, Hansmann B, Balica S, Burlet-Schiltz O, Schmitt AM, Takahara H, Paul C, Serre G, Simon M

J Biol Chem. 2011 Jul 1;286(26):23222-33. doi: 10.1074/jbc.M110.197400. Epub 2011 Apr 29. PMID: 21531719