TopFIND 4.0

Evidence Source

Description Imported from Merops: Merops-evidence: experimental | Merops-type: synthetic | Merops-range: 65-94

Method

Protease identification: VT | Substrate identification: NT

Experimental system

unknown

Perturbation

none

Protease inhibitor(s) used


Directness

unknown

Physiological relevance

unknown

Evidence Code(s)

    inferred from experiment

Database / Laboratory

    - Lab: Hoffmann PR
    - DB: MEROPS

Raw data repository

Evidence for:

0

N-termini

0

C-termini


Publication(s)

Selenoprotein K is a novel target of m-calpain, and cleavage is regulated by Toll-like receptor-induced calpastatin in macrophages.

Huang Z, Hoffmann FW, Norton RL, Hashimoto AC, Hoffmann PR

J Biol Chem. 2011 Oct 7;286(40):34830-8. doi: 10.1074/jbc.M111.265520. Epub 2011 Aug 17. PMID: 21849499