Evidence Source
| Description | Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 28-1822 |
|---|---|
Method |
Protease identification: IN | Substrate identification: MU |
Experimental system |
unknown |
Perturbation |
none |
Protease inhibitor(s) used |
|
Directness |
unknown |
Physiological relevance |
yes |
Evidence Code(s) |
inferred from experiment |
Database / Laboratory |
- Lab: Cryns VL - DB: MEROPS |
Raw data repository |
Evidence for:
0
N-termini
0
C-termini
Publication(s) |
Caspase proteolysis of the integrin beta4 subunit disrupts hemidesmosome assembly, promotes apoptosis, and inhibits cell migration. Werner ME, Chen F, Moyano JV, Yehiely F, Jones JC, Cryns VL J Biol Chem. 2007 Feb 23;282(8):5560-9. Epub 2006 Dec 18. PMID: 17178732 |
|---|