TopFIND 4.0

Evidence Source

Description Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 1-574

Method

Substrate identification: MU

Experimental system

unknown

Perturbation

none

Protease inhibitor(s) used


Directness

unknown

Physiological relevance

yes

Evidence Code(s)

    inferred from experiment

Database / Laboratory

    - Lab: Trotti D
    - DB: MEROPS

Raw data repository

Evidence for:

0

N-termini

0

C-termini


Publication(s)

Caspase-3 cleaves and inactivates the glutamate transporter EAAT2.

Boston-Howes W, Gibb SL, Williams EO, Pasinelli P, Brown RH Jr, Trotti D

J Biol Chem. 2006 May 19;281(20):14076-84. Epub 2006 Mar 27. PMID: 16567804