TopFIND 4.0

Evidence Source

Description Imported from Merops: Cleavage (by caspase-3 and caspase-7) Merops-evidence: experimental | Merops-type: non-physiological | Merops-range: 1-1141

Method


Experimental system

unknown

Perturbation

none

Protease inhibitor(s) used


Directness

unknown

Physiological relevance

none

Evidence Code(s)

    inferred from experiment

Database / Laboratory

    - Lab: Brown MS
    - DB: MEROPS

Raw data repository

Evidence for:

0

N-termini

0

C-termini


Publication(s)

Purification of an interleukin-1 beta converting enzyme-related cysteine protease that cleaves sterol regulatory element-binding proteins between the leucine zipper and transmembrane domains.

Wang X, Pai JT, Wiedenfeld EA, Medina JC, Slaughter CA, Goldstein JL, Brown MS

J Biol Chem. 1995 Jul 28;270(30):18044-50. PMID: 7629113