Evidence Source
Description | Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 2-586 |
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Method |
Substrate identification: NT |
Experimental system |
unknown |
Perturbation |
none |
Protease inhibitor(s) used |
|
Directness |
unknown |
Physiological relevance |
yes |
Evidence Code(s) |
inferred from experiment |
Database / Laboratory |
- Lab: Lieberman J - DB: MEROPS |
Raw data repository |
Evidence for:
0
N-termini
0
C-termini
Publication(s) |
Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis. Zhang D, Beresford PJ, Greenberg AH, Lieberman J Proc Natl Acad Sci U S A. 2001 May 8;98(10):5746-51. Epub 2001 May 1. PMID: 11331782 |
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