Evidence Source
Description | Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 1-189 |
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Method |
Protease identification: NT | Substrate identification: MU |
Experimental system |
unknown |
Perturbation |
none |
Protease inhibitor(s) used |
|
Directness |
unknown |
Physiological relevance |
yes |
Evidence Code(s) |
inferred from experiment |
Database / Laboratory |
- Lab: Alves da Costa C - DB: MEROPS |
Raw data repository |
Evidence for:
0
N-termini
0
C-termini
Publication(s) |
Loss of function of DJ-1 triggered by Parkinson's disease-associated mutation is due to proteolytic resistance to caspase-6. Giaime E, Sunyach C, Druon C, Scarzello S, Robert G, Grosso S, Auberger P, Goldberg MS, Shen J, Heutink P, Pouyssegur J, Pages G, Checler F, Alves da Costa C Cell Death Differ. 2010 Jan;17(1):158-69. doi: 10.1038/cdd.2009.116. Epub . PMID: 19680261 |
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