TopFIND 4.0

Evidence Source

Description Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 1-1339

Method

Substrate identification: MU

Experimental system

unknown

Perturbation

none

Protease inhibitor(s) used


Directness

unknown

Physiological relevance

yes

Evidence Code(s)

    inferred from experiment

Database / Laboratory

    - Lab: Clarke PR
    - DB: MEROPS

Raw data repository

Evidence for:

0

N-termini

0

C-termini


Publication(s)

Cleavage of claspin by caspase-7 during apoptosis inhibits the Chk1 pathway.

Clarke CA, Bennett LN, Clarke PR

J Biol Chem. 2005 Oct 21;280(42):35337-45. Epub 2005 Aug 25. PMID: 16123041